Monitoring of residual disease and guided donor leucocyte infusion after allogeneic bone marrow transplantation by chimaerism analysis with short tandem repeats

RA De Weger, MGJ Tilanus… - British journal of …, 2000 - Wiley Online Library
In this study, we analysed the chimaeric status of peripheral blood leucocytes (PBLs) in
recipients of allogeneic bone marrow transplantation (BMT) with the use of short tandem …

Evaluation of immunomodulatory treatment based on conventional and lineage-specific chimerism analysis in patients with myeloid malignancies after myeloablative …

R Zeiser, A Spyridonidis, R Wäsch, G Ihorst, C Grüllich… - Leukemia, 2005 - nature.com
Both conventional chimerism analysis (CCA) and lineage-specific chimerism analysis (LCA)
have potential pitfalls as diagnostic means for the detection of minimal residual disease after …

Early establishment of hematopoietic chimerism following allogeneic peripheral blood stem cell transplantation in comparison with allogeneic bone marrow …

S Nakao, W Zeng, H Yamazaki, H Wang… - European journal of …, 1999 - Wiley Online Library
To characterize the process of the establishment of complete chimerism after allogeneic
peripheral blood stem cell transplantation (allo‐PBSCT), we determined the origin of …

Anti‐tumour response despite loss of donor chimaerism in patients treated with non‐myeloablative conditioning and allogeneic stem cell transplantation

BR Dey, S McAfee, C Colby, K Cieply… - British journal of …, 2005 - Wiley Online Library
Based on a murine model, we conducted a series of trials of m‐myeloablative human
leucocyte antigen (HLA)‐matched or mismatched related donor stem cell transplantation …

Evaluation of mixed chimerism by in vitro amplification of dinucleotide repeat sequences using the polymerase chain reaction

M Lawler, P Humphries, SR McCann - 1991 - ashpublications.org
The influence of mixed hematopoietic chimerism (MC) after allogeneic bone marrow
transplantation remains unknown. Increasingly sensitive detection methods have shown that …

Use of DNA restriction fragment length polymorphisms to document marrow engraftment and mixed hematopoietic chimerism following bone marrow transplantation

PY Yam, LD Petz, RG Knowlton, RB Wallace… - …, 1987 - journals.lww.com
We have studied the feasibility of using DNA restriction fragment-length polymorphisms
(RFLP) to study marrow engraftment in 27 patients after allogeneic bone marrow …

Follow up of hemopoietic chimerism in individuals given allogeneic hemopoietic stem cell allografts using an immunosuppressive, non-myeloablative conditioning …

GJ Ruiz-Argüelles, B López-Martíneza… - Leukemia & …, 2002 - Taylor & Francis
Thirty consecutive patients were given non-myeloablative stem cell transplants (NST) and
posttransplant chimerism was studied by several methods. In 16 individuals definitive proofs …

Monitoring of hematopoietic chimerism after sex-mismatched allogeneic stem cell transplantation (alloSCT) by dual-color FISH analysis of X and Y chromosomes

D Turkiewicz, E Gorczynska, J Toporski, K Kalwak… - Leukemia research, 2003 - Elsevier
Hematopoietic chimerism was monitored in 18 patients with various diseases after gender-
mismatched allogeneic stem cell transplantation (alloSCT). To detect host and donor cells …

Debate round-table: comments concerning chimerism studies

M Gonzalez, R Lopez-Perez, R Garcia-Sanz… - Leukemia, 2001 - nature.com
Allogeneic stem cell transplantation (allo-SCT) is the treatment of choice for many patients
with hematological malignancies, as well as some non-malignant hematological disorders …

Same‐day determination of chimaeric status in the immediate period following allogeneic bone marrow transplantation

JP Hancock, MF Burgess, NJ Goulden… - British journal of …, 1997 - Wiley Online Library
The accurate and rapid determination of the origin of haemopoietic cells may provide
valuable information as to the aetiology of, and most appropriate therapy for, leucopenia …