Individual studies of the genetics of neural tube defects (NTDs) contain results on a small
number of genes in each report. To identify genetic risk factors for NTDs, we evaluated …

Objective: To study the preconceptual & early conceptional risk factors predisposing to the
development of spina bifida (SB) among Egyptian population. Study design: The study …

Neural tube defects (NTDs) are congenital abnormalities in the central nervous system. The
exact etiology of NTDs is still not determined, but several genetic and epigenetic factors …

Neural tube defects (NTDs) are the most common congenital malformations and are
considered to have a multifactorial origin, having both genetic and environmental …

Myelomeningocele (MMC) affects one in 1000 newborns annually worldwide and each
surviving child faces tremendous lifetime medical and caregiving burdens. Both genetic and …

Neural tube defects (NTDs) occur secondary to failed closure of the neural tube between the
third and fourth weeks of gestation. The worldwide incidence ranges from 0.3 to 200 per …

Aims We investigated the hypothesis that there are interactions between SNPs in folate
metabolism pathway genes and environmental risk factors to the etiology of neural tube …

Neural tube defects (NTD) result from complex mechanisms between genes, nutrition and
environment. The identification of genetic predictors by genome exome sequencing and …

Background: Folic acid and multivitamin supplements ((FAMVS) and genetics involvement is
one of the major roles in the development of neural tube defects (NTDs). Objective: Our prior …

To improve outcomes in fetuses with spina bifida (SB), better understanding is needed of the
molecular drivers of SB and its comorbidities. Pregnant people carrying a fetus with isolated …