[HTML][HTML] Autologous hematopoietic stem cell transplantation for autoimmune diseases: an observational study on 12 years' experience from the European Group for …

D Farge, M Labopin, A Tyndall, A Fassas… - …, 2010 - ncbi.nlm.nih.gov
Background Autologous hematopoietic stem cell transplantation has been used since 1996
for the treatment of severe autoimmune diseases refractory to approved therapies. We …

Autologous haematopoietic stem cell transplants for autoimmune disease–feasibility and transplant-related mortality

A Tyndall, A Fassas, J Passweg… - Bone marrow …, 1999 - nature.com
This ongoing multicentre prospective phase I/II trial enrolled 74 consecutive patients from 22
centres worldwide with severe autoimmune disease, 35 with rheumatological disorders, 31 …

Stem cell transplantation for severe autoimmune diseases: progress and problems

AM Marmont - Haematologica, 1998 - haematologica.org
Abstract Since Morton and Siegel's epochal experiments 30 years ago animal models have
been successfully utilized both for transfer and resolution of autoimmune diseases (AID) …

Autologous stem cell transplantation in autoimmune diseases

J Passweg, A Tyndall - Seminars in hematology, 2007 - Elsevier
Since 1996, approximately 1,000 patients have received an autologous hematopoietic stem
cell transplant (HSCT) as treatment for a severe autoimmune disease (AD). The European …

Autologous hematopoietic stem cell transplantation for autoimmune diseases

A Gratwohl, J Passweg, C Bocelli-Tyndall… - Bone marrow …, 2005 - nature.com
Experimental data and early phase I/II studies suggest that high-dose chemotherapy
followed by autologous hematopoietic stem cell transplantation (HSCT) can arrest …

Haematopoietic stem cell transplantation in the treatment of severe autoimmune disease: results from phase I/II studies, prospective randomized trials and future …

A Tyndall, R Saccardi - Clinical & Experimental Immunology, 2005 - academic.oup.com
Around 700 patients have received an autologous haematopoietic stem cell transplant
(HSCT) as treatment for a severe autoimmune disease (AD). The majority of these have …

Haematopoietic stem cell transplants: principles and indications

K Balassa, R Danby, V Rocha - British Journal of Hospital …, 2019 - magonlinelibrary.com
Haematopoietic stem cell transplantation was proposed as a treatment strategy just over 60
years ago. Owing to great advances in the field, haematopoietic stem cell transplantation …

Clinically demonstrable anti-autoimmunity mediated by allogeneic immune cells favorably affects outcome after stem cell transplantation in human autoimmune …

W Hinterberger, M Hinterberger-Fischer… - Bone Marrow …, 2002 - nature.com
To determine the role of allogeneic, autologous and syngeneic hemopoietic stem cell
transplantation (SCTx) as a treatment for severe autoimmune disease (AID) we performed a …

Allogeneic hematopoietic SCT for patients with autoimmune diseases

T Daikeler, T Hügle, D Farge, M Andolina… - Bone marrow …, 2009 - nature.com
Allogeneic hematopoietic SCT (HSCT) has been used as treatment for single patients with
autoimmune diseases (AD). To summarise currently available information, we analyzed all …

[HTML][HTML] Autologous haematopoietic stem cell transplantation (aHSCT) for severe resistant autoimmune and inflammatory diseases–a guide for the generalist

JA Snowden, B Sharrack, M Akil, DG Kiely, A Lobo… - Clinical Medicine, 2018 - Elsevier
Autologous haematopoietic stem cell transplantation (aHSCT) is commonly used for the
treatment of haematological cancers, but is increasingly used in the treatment of patients …