The delay of aging and healthy life extension is a primary concern of modern gerontological
research. Based on theoretical assumptions and empirical findings, a number of bioactive …

Hormesis, the beneficial effects of mild stress exposures, is a well documented phenomenon
in a range of organisms. The documentation mainly relies on relatively simple and controlled …

The aging of the population brings new heath challenges, and in particular, the need to
implement suitable pro-healthy aging interventions. This paper discusses the potential of …

This paper provides a broad overview of hormesis, a specific type of biphasic dose
response, its historical and scientific foundations as well as its biomedical applications …

The field of toxicology adopted the threshold dose response in the early decades of the 20th
century. The model was rapidly incorporated into governmental regulatory assessment …

Biology of aging is well understood at a descriptive level. Based on these data,
biogerontological research is now able to develop various possibilities for intervention. A …

Adaptation is a fundamental biological concept at the core of evolutionary biology and the
process of natural selection. It is also a central feature within the lives of individuals …

Hormesis refers to the ability of a chemical or physical agent to condition the physiological
state of an organism to tolerate stress with low doses of otherwise harmful agents …

A critical review of various methods of testing of geroprotectors (antiaging compounds or
physical factors) in experiments on cultured cells is presented. Some cytogerontological …

This paper addresses how long lifespan can be extended via multiple interventions, such as
dietary supplements [eg, curcumin, resveratrol, sulforaphane, complex phytochemical …