Human amniotic fluid as a potential new source of organ specific precursor cells for future regenerative medicine applications

S Da Sacco, S Sedrakyan, F Boldrin… - The Journal of …, 2010 - auajournals.org
Purpose: Human amniotic fluid contains multiple cell types, including pluripotent and
committed progenitor cells, and fully differentiated cells. We characterized various cell …

Renal differentiation of amniotic fluid stem cells

L Perin, S Giuliani, D Jin, S Sedrakyan… - Cell …, 2007 - Wiley Online Library
Objectives: The role of stem cells in regenerative medicine is evolving rapidly. Here, we
describe the application, for kidney regeneration, of a novel non‐genetically modified stem …

Amniotic fluid as a source of pluripotent and multipotent stem cells for organ regeneration

S Da Sacco, RE De Filippo, L Perin - Current Opinion in Organ …, 2011 - journals.lww.com
Amniotic fluid as a source of pluripotent and multipotent st... : Current Opinion in Organ
Transplantation Amniotic fluid as a source of pluripotent and multipotent stem cells for organ …

Induction of mesenchymal/epithelial marker expression in human amniotic fluid stem cells

N Siegel, A Valli, C Fuchs, M Rosner… - Reproductive …, 2009 - Elsevier
Although dialysis and transplantation are widely applied therapies for renal failure,
drawbacks such as morbidity, shortage of compatible organs and high cost are limiting …

Characterization of human amniotic fluid stem cells and their pluripotential capability

L Perin, S Sedrakyan, S Da Sacco, R De Filippo - Methods in cell biology, 2008 - Elsevier
Over the past decade, there has been ever‐increasing emphasis placed on stem cells and
their potential role in regenerative medicine for reconstruction of bio‐artificial tissues and …

Stepwise renal lineage differentiation of mouse embryonic stem cells tracing in vivo development

M Nishikawa, N Yanagawa, N Kojima, S Yuri… - Biochemical and …, 2012 - Elsevier
The in vitro derivation of renal lineage progenitor cells is essential for renal cell therapy and
regeneration. Despite extensive studies in the past, a protocol for renal lineage induction …

Urine of preterm neonates as a novel source of kidney progenitor cells

FO Arcolino, S Zia, K Held… - Journal of the …, 2016 - journals.lww.com
In humans, nephrogenesis is completed prenatally, with nephrons formed until 34 weeks of
gestational age. We hypothesized that urine of preterm neonates born before the completion …

[HTML][HTML] Human embryonic stem cells differentiate into functional renal proximal tubular–like cells

K Narayanan, KM Schumacher, F Tasnim… - Kidney international, 2013 - Elsevier
Renal cells are used in basic research, disease models, tissue engineering, drug screening,
and in vitro toxicology. In order to provide a reliable source of human renal cells, we …

[PDF][PDF] Evidence of in vitro preservation of human nephrogenesis at the single-cell level

N Pode-Shakked, R Gershon, G Tam, D Omer… - Stem Cell Reports, 2017 - cell.com
During nephrogenesis, stem/progenitor cells differentiate and give rise to early nephron
structures that segment to proximal and distal nephron cell types. Previously, we …

Expression of stem cell markers in the human fetal kidney

S Metsuyanim, O Harari-Steinberg, E Buzhor, D Omer… - PloS one, 2009 - journals.plos.org
In the human fetal kidney (HFK) self-renewing stem cells residing in the metanephric
mesenchyme (MM)/blastema are induced to form all cell types of the nephron till 34th week …