The forgotten men: rising rates of male infertility urgently require new approaches for its prevention, diagnosis and treatment

V Ravitsky, S Kimmins - Biology of reproduction, 2019 - academic.oup.com
Over the past 40 years, sperm counts worldwide have halved and sperm quality has
declined alarmingly with 1 in 20 men currently facing reduced fertility [1]. Potential causes of …

Male infertility is a women's health issue—research and clinical evaluation of male infertility is needed

KA Turner, A Rambhatla, S Schon, A Agarwal… - Cells, 2020 - mdpi.com
Infertility is a devastating experience for both partners as they try to conceive. Historically,
when a couple could not conceive, the woman has carried the stigma of infertility; however …

Not every sperm is sacred; a perspective on male infertility

RJ Aitken - MHR: Basic science of reproductive medicine, 2018 - academic.oup.com
This article is a personal perspective on male infertility, a condition that is not only extremely
prevalent but also a major reason for couples to resort to ART. The introduction of ICSI as a …

[HTML][HTML] Limits of current male fertility testing

S Oehninger, W Ombelet - Fertility and Sterility, 2019 - Elsevier
In the current approach to male fertility testing, basic semen analysis has limitations as a
predictor of fertility status, and the technology is fraught with variability. Nonetheless, it …

Lack of trusted diagnostic tools for undetermined male infertility

S Pandruvada, R Royfman, TA Shah… - Journal of Assisted …, 2021 - Springer
Semen analysis is the cornerstone of evaluating male infertility, but it is imperfect and
insufficient to diagnose male infertility. As a result, about 20% of infertile males have …

[HTML][HTML] Semen analysis in 21st century medicine: the need for sperm function testing

DJ Lamb - Asian journal of andrology, 2010 - ncbi.nlm.nih.gov
Sperm function testing, once commonly performed for the infertile couple before employing
assisted reproductive technology (ART), has fallen out of favour in many reproductive …

Contemporary management of male infertility

PJ Stahl, DS Stember, M Goldstein - Annual review of medicine, 2012 - annualreviews.org
Knowledge of normal male reproductive function and familiarity with the diagnostic
evaluation and treatment of male subfertility is beneficial for most physicians. Male …

Infertility in men: advances towards a comprehensive and integrative strategy for precision theranostics

M Assidi - Cells, 2022 - mdpi.com
Male infertility is an increasing and serious medical concern, though the mechanism
remains poorly understood. Impaired male reproductive function affects approximately half …

Strategies for the infertile man

S Oehninger - Seminars in reproductive medicine, 2001 - thieme-connect.com
Male infertility is one of the most common, identifiable causes of human reproductive failure.
Although considerable progress has been made toward understanding sperm physiology …

The present crisis in male reproductive health: an urgent need for a political, social, and research roadmap

C De Jonge, CLR Barratt - Andrology, 2019 - Wiley Online Library
Background There is a global crisis in male reproductive health. Evidence comes from
globally declining sperm counts and increasing male reproductive system abnormalities …