Silicosis is a fatal pulmonary fibrotic disorder characterized by accumulation of fibroblasts
and myofibroblasts and deposition of extracellular matrix proteins. MiR-449a is a potential …

Silicosis is a kind of chronic, progressive and incurable lung fibrotic diseases with largely
unknown and complex pathogenesis and molecular mechanisms. Mounting evidence …

Silicosis is a kind of irreversible pulmonary fibrosis induced by the long-term inhalation of
silica particles. The therapeutic strategy based on the microRNAs might be an effective way …

Silicosis is a refractory pneumoconiosis of unknown etiology that is characterized by diffuse
lung fibrosis, and microRNA (miRNA) dysregulation is connected to silicosis. Emerging …

Silicosis is a very serious occupational disease and it features pathological manifestations of
inflammatory infiltration, excessive proliferation of fibroblasts and massive depositions of the …

Silicosis is an incurable occupational disease associated with inflammation, fibroblast
proliferation and the accumulation of extracellular matrix in lung tissues. The dysregulation …

Silicosis is an incurable occupational disease, and its pathological feature is diffuse
pulmonary fibrosis. Pulmonary epithelial‐mesenchymal transition (EMT) is one of the …

Silicosis is associated with fibroblast proliferation and extracellular matrix deposition in lung
tissues. The dysregulation of miR-1224-5p has been implicated in several human cancers; …

Silicosis is a devastating interstitial lung disease arising from long-term exposure to
inhalable silica. Regrettably, no therapy currently can effectively reverse the silica-induced …

To identify microRNAs (miRNAs, miRs) with potential roles in lung fibrogenesis, we
performed genome-wide profiling of miRNA expression in lung tissues from a silica-induced …