To determine whether nifedipine or diltiazem affect digoxin kinetics, glycoside plasma
concentrations and renal excretion were measured before and during dosing in 23 patients …

Nifedipine has been reported either to decrease or not to affect digoxin elimination. We
studied the effect of oral nifedipine on steady‐state digoxin concentrations and renal …

Diltiazem has been reported to decrease or not to affect digoxin elimination. The effects of
diltiazem on steady state concentrations of digoxin was evaluated in eleven patients with …

The effect of diltiazem on digoxin serum concentration was evaluated in 9 patients who had
been treated chronically for heart disease with digoxin, 0.25 mg/day. The indications for …

Drug interactions with digoxin are being increasingly recognized. Some calcium antagonists
have been shown to alter digoxin kinetics and changes in digoxin dosage have been …

The effect of verapamil on the pharmacokinetics of digoxin was studied in 49 patients with
chronic atrial fibrillation. A dose of 240 mg/day of verapamil was given to the patients who …

The effects on the steady‐state digoxin pharmacokinetics of verapamil (240 mg/day) and a
new dihydropyridine calcium channel blocker, isradipine (15 mg/day), were compared …

The effect of oral amlodipine on steady-state digoxin concentrations and renal clearance
was studied in 21 healthy male subjects. After 2-week digitalization (digoxin, 0.375 mg/day) …

Seven healthy volunteers received a single 1.0‐mg dose of intravenous digoxin in a drug‐
free control trial and again during concurrent therapy with therapeutic doses of quinidine …

The steady‐state pharmacokinetics of oral digoxin in eight hospitalized patients was
compared upon their admission with marked right‐sided congestive heart failure and later …