E-cadherin is a transmembrane glycoprotein that mediates calcium-dependent, homotypic
cell–cell adhesion and plays a role in maintaining the normal phenotype of epithelial cells …

E-and N-cadherin are calcium-dependent cell adhesion molecules that mediate cell–cell
adhesion and also modulate cell migration and tumor invasiveness. The loss of E-cadherin …

The loss of E‐cadherin expression or function in epithelial carcinomas has long been
thought as a primary reason for disruption of tight epithelial cell‐cell contacts and release of …

Disruption of cell–cell adhesion, which is essential for the maintenance of epithelial plasticity
and is mediated by a class of proteins called cadherins, is an initial event in the progression …

Background Alterations in the cadherin-catenin adhesion complexes are involved in tumor
initiation, progression and metastasis. However, the functional implication of distinct …

Cell–cell adhesion is an elementary process in normal epithelial cellular architecture.
Several studies have shown the role mediated by cadherins in this process, besides their …

Calcium-dependent cell adhesion molecules (cadherins) are involved in maintaining the
epithelial structure of a number of tissues including the mammary gland. In breast and other …

Abstract E-cadherin (E-cad) is a subclass of the cadherin family that plays a major role in
maintenance of intercellular junctions in epithelial tissues. In order to explore the correlation …

E-cadherin is a transmembrane glycoprotein that mediates calcium-dependent, homotypic
cell-cell adhesion and plays an important role in maintaining the normal phenotype of …

In several cancers, including breast cancer, loss of E-cadherin expression is correlated with
a loss of the epithelial phenotype and with a gain of invasiveness. Cells that have lost E …