N-cadherin promotes motility in human breast cancer cells regardless of their E-cadherin expression
MT Nieman, RS Prudoff, KR Johnson… - The Journal of cell …, 1999 - rupress.org
E-cadherin is a transmembrane glycoprotein that mediates calcium-dependent, homotypic
cell–cell adhesion and plays a role in maintaining the normal phenotype of epithelial cells …
cell–cell adhesion and plays a role in maintaining the normal phenotype of epithelial cells …
Exogenous expression of N-cadherin in breast cancer cells induces cell migration, invasion, and metastasis
RB Hazan, GR Phillips, RF Qiao, L Norton… - The Journal of cell …, 2000 - rupress.org
E-and N-cadherin are calcium-dependent cell adhesion molecules that mediate cell–cell
adhesion and also modulate cell migration and tumor invasiveness. The loss of E-cadherin …
adhesion and also modulate cell migration and tumor invasiveness. The loss of E-cadherin …
Cadherin switch in tumor progression
RB Hazan, RUI Qiao, R Keren… - Annals of the New …, 2004 - Wiley Online Library
The loss of E‐cadherin expression or function in epithelial carcinomas has long been
thought as a primary reason for disruption of tight epithelial cell‐cell contacts and release of …
thought as a primary reason for disruption of tight epithelial cell‐cell contacts and release of …
Molecular mechanisms controlling E-cadherin expression in breast cancer
S Baranwal, SK Alahari - Biochemical and biophysical research …, 2009 - Elsevier
Disruption of cell–cell adhesion, which is essential for the maintenance of epithelial plasticity
and is mediated by a class of proteins called cadherins, is an initial event in the progression …
and is mediated by a class of proteins called cadherins, is an initial event in the progression …
Functional characterization of E-and P-cadherin in invasive breast cancer cells
D Sarrió, J Palacios, M Hergueta-Redondo… - BMC cancer, 2009 - Springer
Background Alterations in the cadherin-catenin adhesion complexes are involved in tumor
initiation, progression and metastasis. However, the functional implication of distinct …
initiation, progression and metastasis. However, the functional implication of distinct …
Extracellular cleavage and shedding of P-cadherin: a mechanism underlying the invasive behaviour of breast cancer cells
AS Ribeiro, A Albergaria, B Sousa, AL Correia… - Oncogene, 2010 - nature.com
Cell–cell adhesion is an elementary process in normal epithelial cellular architecture.
Several studies have shown the role mediated by cadherins in this process, besides their …
Several studies have shown the role mediated by cadherins in this process, besides their …
N-cadherin promotes adhesion between invasive breast cancer cells and the stroma
RB Hazan, L Kang, BP Whooley… - Cell adhesion and …, 1997 - Taylor & Francis
Calcium-dependent cell adhesion molecules (cadherins) are involved in maintaining the
epithelial structure of a number of tissues including the mammary gland. In breast and other …
epithelial structure of a number of tissues including the mammary gland. In breast and other …
Expression of E-cadherin cell adhesion molecules in human breast cancer tissues and its relationship to metastasis
H Oka, H Shiozaki, K Kobayashi, M Inoue, H Tahara… - Cancer research, 1993 - AACR
Abstract E-cadherin (E-cad) is a subclass of the cadherin family that plays a major role in
maintenance of intercellular junctions in epithelial tissues. In order to explore the correlation …
maintenance of intercellular junctions in epithelial tissues. In order to explore the correlation …
Expression of N-cadherin by human squamous carcinoma cells induces a scattered fibroblastic phenotype with disrupted cell-cell adhesion.
S Islam, TE Carey, GT Wolf, MJ Wheelock… - The Journal of cell …, 1996 - rupress.org
E-cadherin is a transmembrane glycoprotein that mediates calcium-dependent, homotypic
cell-cell adhesion and plays an important role in maintaining the normal phenotype of …
cell-cell adhesion and plays an important role in maintaining the normal phenotype of …
Cadherin-11 is expressed in invasive breast cancer cell lines
MJ Pishvaian, CM Feltes, P Thompson… - Cancer research, 1999 - AACR
In several cancers, including breast cancer, loss of E-cadherin expression is correlated with
a loss of the epithelial phenotype and with a gain of invasiveness. Cells that have lost E …
a loss of the epithelial phenotype and with a gain of invasiveness. Cells that have lost E …