Diagnosis and classification of immune-mediated thrombocytopenia

E Lo, S Deane - Autoimmunity reviews, 2014 - Elsevier
Immune thrombocytopenia, or ITP, has been recognized as a clinical entity for centuries, and
the importance of humoral mechanisms in the pathophysiology of ITP has been recognized …

Primary immune thrombocytopenia: novel insights into pathophysiology and disease management

A Singh, G Uzun, T Bakchoul - Journal of Clinical Medicine, 2021 - mdpi.com
Immune thrombocytopenia (ITP) is an autoimmune disorder defined by a significantly
reduced number of platelets in blood circulation. Due to low levels of platelets, ITP is …

Current treatment options for primary immune thrombocytopenia

A Salama - Expert review of hematology, 2011 - Taylor & Francis
Traditional treatment of primary (idiopathic) immune thrombocytopenia (ITP) predominantly
consists of immune suppression and/or modulation. In addition, many treated patients …

Immune thrombocytopenia

A Cuker, DB Cines - Hematology 2010, the American Society …, 2010 - ashpublications.org
Immune thrombocytopenia (ITP) comprises a heterogeneous group of disorders
characterized by autoimmune-mediated platelet destruction and impairment of …

The many facets of immune-mediated thrombocytopenia: Principles of immunobiology and immunotherapy

T Moulinet, A Moussu, L Pierson, S Pagliuca - Blood Reviews, 2023 - Elsevier
Immune thrombocytopenia (ITP) is a rare autoimmune condition, due to peripheral platelet
destruction through antibody-dependent cellular phagocytosis, complement-dependent …

Primary and secondary immune thrombocytopenia (ITP): Time for a rethink

TJ González-López, D Provan, A Bárez… - Blood Reviews, 2023 - Elsevier
There are not many publications that provide a holistic view of the management of primary
and secondary ITP as a whole, reflecting the similarities and differences between the two …

Update on diagnosis and treatment of immune thrombocytopenia

R Sandal, K Mishra, A Jandial, KK Sahu… - Expert review of …, 2021 - Taylor & Francis
Background Immune thrombocytopenia (ITP) is a heterogeneous acquired disorder
characterized by isolated thrombocytopenia whose exact pathogenesis is not yet clear …

Immune thrombocytopenia: recent progress in pathophysiology and treatment

U Abadi, O Yarchovsky-Dolberg… - Clinical and Applied …, 2015 - journals.sagepub.com
Immune thrombocytopenia (ITP) is a rare autoimmune disorder with an incidence of 3 to 5
per 100 000 individuals. In children, the disease is self-limited and is most commonly virus …

Current management of immune thrombocytopenia

CE Neunert - Hematology 2013, the American Society of …, 2013 - ashpublications.org
Immune thrombocytopenia (ITP) is an autoimmune-mediated condition that results from
antibody-mediated destruction of platelets and impaired megakaryocyte platelet production …

Current management of primary immune thrombocytopenia

D Provan, AC Newland - Advances in therapy, 2015 - Springer
Primary immune thrombocytopenia is an autoimmune disorder of unknown cause affecting
both children and adults. The low peripheral blood platelet count is caused by premature …