This prospective, randomized, multicenter, controlled trial was designed to evaluate the
efficacy and safety of intravenous ganciclovir for the treatment of peripheral cytomegalovirus …

Background Cytomegalovirus retinitis, a sight-threatening infection associated with the
acquired immunodeficiency syndrome (AIDS), currently requires lifelong intravenous …

To determine whether therapeutic intravitreal concentrations of ganciclovirare achieved after
intravenous administration, vitreous samples were obtained intraoperatively from 23 eyes of …

Retinitis is the commonest clinical manifestation of cytomegalovirus (CMV) infection in
patients with AIDS. Untreated patients generally experience progressive involvement of the …

Background: Cytomegalovirus (CMV) retinitis is the most common opportunistic ocular
infection in AIDS patients, and frequently leads to blindness if untreated. Intravitreal …

Background Valganciclovir is an orally administered prodrug that is rapidly hydrolyzed to
ganciclovir. We compared the effects of oral valganciclovir with those of intravenous …

We report the first randomized prospective comparative study of long‐term maintenance
ganciclovir (9‐[2‐hydroxy‐1‐(hydroxymethyl) ethoxymethyl] guanine, BW759U, DHPG) …

Objective To assess the role of intravitreal administration of high doses of ganciclovir as a
supplement and alternative to intravenous administration in the treatment of cytomegalovirus …

AIDS patients with newly diagnosed cytomegalovirus (CMV) retinitis who had just completed
a 14-day course of ganciclovir induction therapy were randomly assigned to an alternating …

A 15-month prospective study of 109 patients with the acquired immune deficiency
syndrome (AIDS) or AIDS-related complex (ARC) was conducted. Cytomegalovirus (CMV) …