Cryptococcus gattii isolates from the British Columbia cryptococcosis outbreak induce less protective inflammation in a murine model of infection than Cryptococcus …

PY Cheng, A Sham, JW Kronstad - Infection and immunity, 2009 - Am Soc Microbiol
The fungal pathogen Cryptococcus neoformans causes approximately one million cases of
cryptococcosis per year in people with AIDS. In contrast, the related species C. gattii is …

What makes Cryptococcus gattii a pathogen?

E Bielska, RC May - FEMS yeast research, 2016 - academic.oup.com
Cryptococcosis is an invasive fungal infection of humans and other animals, typically caused
by the species Cryptococcus neoformans in patients with impaired immunity. However, there …

Cryptococcus gattii Induces a Cytokine Pattern That Is Distinct from Other Cryptococcal Species

T Schoffelen, MT Illnait-Zaragozi, LAB Joosten… - PloS one, 2013 - journals.plos.org
Understanding more about the host's immune response to different Cryptococcus spp. will
provide additional insight into the pathogenesis of cryptocococcis. We hypothesized that the …

Cryptococcus gattii Virulence Composite: Candidate Genes Revealed by Microarray Analysis of High and Less Virulent Vancouver Island Outbreak Strains

P Ngamskulrungroj, J Price, T Sorrell, JR Perfect… - PLoS …, 2011 - journals.plos.org
Human and animal cryptococcosis due to an unusual molecular type of Cryptococcus gattii
(VGII) emerged recently on Vancouver Island, Canada. Unlike C. neoformans, C. gattii …

The emergence of Cryptococcus gattii in British Columbia and the Pacific Northwest

KH Bartlett, SE Kidd, JW Kronstad - Current infectious disease reports, 2008 - Springer
An unprecedented emergence of cryptococcal infections in animals and otherwise healthy
humans was recognized in 1999 on the east coast of Vancouver Island, British Columbia …

Immune dysfunction in HIV-seronegative, Cryptococcus gattii meningitis

AE Brouwer, AA Siddiqui, MI Kester, KCE Sigaloff… - Journal of Infection, 2007 - Elsevier
The pathophysiology of meningitis caused by Cryptococcus gattii in apparently
immunocompetent individuals remains unclear. We measured multiple cytokines in CSF …

Cryptococcus: History, Epidemiology and Immune Evasion

I Diniz-Lima, LM Fonseca, EB Silva-Junior… - Applied Sciences, 2022 - mdpi.com
Cryptococcosis is a disease caused by the pathogenic fungi Cryptococcus neoformans and
Cryptococcus gattii, both environmental fungi that cause severe pneumonia and may even …

Virulence in Cryptococcus species

H Ma, RC May - Advances in applied microbiology, 2009 - Elsevier
Cryptococcus neoformans and Cryptococcus gattii are the cause of life-threatening
meningoencephalitis in immunocompromised and immunocompetent individuals …

The primary target organ of Cryptococcus gattii is different from that of Cryptococcus neoformans in a murine model

P Ngamskulrungroj, Y Chang, E Sionov… - MBio, 2012 - Am Soc Microbiol
Cryptococcosis is caused by the opportunistic pathogen Cryptococcus neoformans or by the
primary pathogen Cryptococcus gattii. Epidemiological studies suggest that patients infected …

Depletion of murine CD8+ T cells in vivo decreases pulmonary clearance of a moderately virulent strain of Cryptococcus neoformans

CH Mody, GH Chen, C Jackson… - The Journal of …, 1993 - translationalres.com
Host defense mechanisms to the important fungal pathogen Cryptococcus neoformans are
complex and incompletely understood. From in vitro studies, we could expect CD8+ T cells …