LDL combines with oxygen free radicals on the surface of endothelium, which could lead to
the formation of ox-LDL. Ox-LDL then is taken up by antigen presenting cells (APC) such as …

Background OxLDL plays a major role in the initiation and progression of atherosclerotic
lesions even though further factors are needed to promote fibrous cap rupture and …

OBJECTIVE: To investigate the association between proliferative response of T cells and
plaque stability in coronary heart disease. METHODS: A total of 66 subjects were recruited …

Several studies have implicated adaptive immunity, particularly altered T lymphocyte
function, in the pathogenesis of acute coronary syndromes (ACS)(Figure 1). 1, 2 A variety of …

Adaptive immune responses are involved in all stages of atherosclerotic plaque
development, including plaque complication (ie, rupture, ulceration, etc), which may lead to …

Organisms have developed multiple host defence mechanisms through the millennia to deal
with invading pathogens. The innate immune system constitutes one such protective …

Abstracts Inflammatory and immunologic mechanisms are important for the initiation and the
progression of atherosclerotic lesions. OxLDL and HSP-60 antigens are involved in the …

Accumulating evidence suggests that the Th1 immune response induced by various
antigens such as oxidized low density lipoprotein (ox-LDL) and heat shock proteins (HSPs) …

Background—CD4+ CD28null T cells are present in increased numbers in the peripheral
blood of patients with acute coronary syndrome (ACS) compared with patients with chronic …

Recent evidence has suggested an association between Chlamydia pneumoniae infection
and coronary atherosclerosis. A significant association has also been detected between …