DNA demethylation and remethylation are crucial for reprogramming of the differentiated
parental/somatic genome in the recipient ooplasm upon somatic cell nuclear transfer. Here …

Early embryonic development in the pig requires DNA methylation remodeling of the
maternal and paternal genomes. Aberrant remodeling, which can be exasperated by in vitro …

Active demethylation of the paternal genome but not of the maternal genome occurs in
fertilized mouse, rat, pig, and bovine zygotes. To study whether this early demethylation …

There is species divergence in control of DNA methylation during preimplantation
development. The exact pattern of methylation in the bovine embryo has not been …

DNA methylation reprogramming plays important roles in mammalian embryogenesis.
Mammalian somatic cell nuclear transfer (SCNT) embryos with reprogramming defects fail to …

The epigenetic reprogramming of the donor cell nucleus is an important factor in the
development of embryos and production of normal offspring derived by somatic cell nuclear …

Alterations to DNA methylation have been attributed to in vitro culture and may affect normal
embryo development. We chose to analyze DNA methylation reprogramming in the rabbit …

Methylation of DNA is the most commonly studied epigenetic mechanism of developmental
competence and somatic cell nuclear transfer (SCNT). Previous studies of epigenetics and …

In mammals, active demethylation of cytosine methylation in the sperm genome prior to
forming a functional zygotic nucleus is thought to be a function of the oocyte cytoplasm …

Global reduction of DNA methylation, a part of genome reprogramming processes, occurs in
a gradual manner until before implantation and is recognized as a conserved process in …