Cytokines in the pathogenesis of atherosclerosis

JL Young, P Libby, U Schönbeck - Thrombosis and …, 2002 - thieme-connect.com
Research during the last two decades established atheromatous lesions as active sites of
inflammation and immune responses, contrasting to the traditional view of atherosclerosis as …

Cytokines in atherosclerosis: pathogenic and regulatory pathways

A Tedgui, Z Mallat - Physiological reviews, 2006 - journals.physiology.org
Atherosclerosis is a chronic disease of the arterial wall where both innate and adaptive
immunoinflammatory mechanisms are involved. Inflammation is central at all stages of …

Interleukins in atherosclerosis: molecular pathways and therapeutic potential

JH Von der Thüsen, J Kuiper, TJC Van Berkel… - Pharmacological …, 2003 - ASPET
Interleukins are considered to be key players in the chronic vascular inflammatory response
that is typical of atherosclerosis. Thus, the expression of proinflammatory interleukins and …

[HTML][HTML] Cytokines in atherosclerosis: Key players in all stages of disease and promising therapeutic targets

DP Ramji, TS Davies - Cytokine & growth factor reviews, 2015 - Elsevier
Atherosclerosis, a chronic inflammatory disorder of the arteries, is responsible for most
deaths in westernized societies with numbers increasing at a marked rate in developing …

Macrophages and immune cells in atherosclerosis: recent advances and novel concepts

C Cochain, A Zernecke - Basic research in cardiology, 2015 - Springer
Atherosclerotic lesion-related thrombosis is the major cause of myocardial infarction and
stroke, which together constitute the leading cause of mortality worldwide. The inflammatory …

Role of inflammatory cytokines in genesis and treatment of atherosclerosis

E Biros, JE Reznik, CS Moran - Trends in Cardiovascular Medicine, 2022 - Elsevier
Atherosclerosis demonstrates an increased rate of vascular smooth muscle cells (VSMC)
plasticity characterized by switching from the differentiated contractile phenotype to a de …

Interferon-γ and atherosclerosis: pro-or anti-atherogenic?

EJ Harvey, DP Ramji - Cardiovascular research, 2005 - academic.oup.com
Atherosclerosis is considered to be a form of chronic inflammation governed by a complex
network of inter-and intra-cellular signaling pathways. The pleiotropic cytokine interferon-γ …

Macrophages in vascular inflammation and atherosclerosis

C Cochain, A Zernecke - Pflügers Archiv-European Journal of Physiology, 2017 - Springer
Atherosclerosis is characterized by lipid accumulation and chronic inflammation of the
arterial wall, and its main complications—myocardial infarction and ischemic stroke …

Atherosclerosis and immunity: a perspective

F Abdolmaleki, SMG Hayat, V Bianconi… - Trends in cardiovascular …, 2019 - Elsevier
Atherosclerosis is an inflammatory and multifaceted disorder resulting from the accumulation
of lipid droplets and several types of immune cells, including macrophages, T and B …

Atherosclerosis and interferon-γ: new insights and therapeutic targets

I Voloshyna, MJ Littlefield, AB Reiss - Trends in cardiovascular medicine, 2014 - Elsevier
Atherosclerosis is considered to be a chronic inflammatory disease of the arterial wall.
Atherogenesis is accompanied by local production and release of inflammatory mediators …