In the past few years, inflammation has emerged as a major driving force of atherosclerotic
lesion development. It is now well-established that from early lesion to vulnerable plaque …

In atherosclerosis, the accumulation of apolipoprotein B-lipoproteins in the matrix beneath
the endothelial cell layer of blood vessels leads to the recruitment of monocytes, the cells of …

Atherosclerosis is a chronic inflammatory disease that is characterized by the development
of fibrotic plaques in the arterial wall. The disease exhibits a complex aetiology and its …

Inflammation plays a key role in the initiation and progression of atherosclerosis and can be
caused by multiple agents, including increased concentration of circulating low-density …

Despite marked advances in medical research over the past several decades,
cardiovascular disease continues to be the primary cause of morbidity and mortality …

Atherosclerosis is now recognized as an inflammatory/immunomodulatory reaction to the
presence of oxidized low-density lipoproteins within the arterial wall, often times in the …

The notion of atherosclerosis as a chronic inflammatory disease has intensified research on
the role of cytokines and the way these molecules act and interact to initiate and sustain …

Atherosclerosis is a lipid-driven inflammatory disease of the arterial intima in which the
balance of pro-inflammatory and inflammation-resolving mechanisms dictates the final …

The designation of atherosclerosis as a chronic inflammatory process represents an
interesting paradigmatic shift for cardiologists. The plasma concentrations of interleukin-6 …

Inflammation orchestrates each stage of the life cycle of atherosclerotic plaques. Indeed,
inflammatory mediators likely link many traditional and emerging risk factors with …