In certain animal tumor systems, transferrin appears to play a key role in the cellular uptake
of radiogallium. This process is mediated by a transferrin receptor which is present on tumor …

Human melanoma cells were incubated with 67 Ga-citrate, a mixture of 67 Ga-citrate and
transferrin, 67 Ga-transferrin and 67 Ga-transferrin-125 I. It was found that there was a …

In order to evaluate the mechanisms which facilitate the transfer of 67 Ga from transferrin in
plasma to intracellular binding sites, lactoferrin, a glycoprotein with high affinity for 67 Ga …

The mechanism of radiogallium uptake into tumor in vivo has been investigated using the
canine transmissible venereal tumor (TVT) as a model. The blood clearance and uptake in …

This paper reviews the evidence regarding transferrin's participation in the mechanism by
which tumor cells attain high concentrations of 67 Ga. Studies using cultured tumor cells …

When injected at tracer levels into the blood, radiogallium as 67 Ga-citrate binds to, and is
transported to the site of the tumor by, transferrin. The process by which transferrin-bound …

We studied the tumor uptake of [67Ga] citrate,[59Fe] citrate, and 125I-labeled transferrin (TF)
by the in vitro growth form of EMT-6, a sarcoma-like mammary tumor of BALB/c mice. In …

In several mouse tumour models iron given parenterally not only inhibited the transport of
67Ga by plasma transferrin but also accelerated the binding of 67Ga in tumour tissue …

The mechanism of tumor localization of gallium-67 (67 Ga) is not known with certainty,
although much information has been derived regarding the biodistribution and subcellular …

The relationship was studied between the number of transferrin-receptor positive cells and
in vitro uptake of 67 Ga and 125 I-labeled transferrin in human cell lines, including two …