B lymphocytes are regarded as professional antigen-presenting cells (APCs) despite their
primary role in humoral immunity. Over the last two decades, studies designed to define the …

Several characteristics confer on B cells the ability to present antigen efficiently:(1) they can
find T cells in secondary lymphoid organs shortly after antigen entrance,(2) BCR-mediated …

In this study, we ask whether antigen presentation can be effected by antigen-activated B
cells. Antigen-dependent in vitro proliferation of T cells from mice primed with SRBC or …

B cells have been known for their ability to present antigens to T cells for almost 40 years.
However, the precise roles of B cell antigen presentation in various immune responses are …

B cells have been long studied for their role and function in the humoral immune system.
Apart from generating antibodies and an antibody-mediated memory response against …

Burnet's original description of the clonal selection hypothesis of antibody production
included many prescient predictions of how 'lymphocytes carrying reactive sites' for foreign …

Publisher Summary This chapter reviews the evidence in favor of the concept that B cells
can serve as antigen-presenting accessory cells to T cells of the helper/inducer subset as …

Small, resting B lymphocytes are driven into the cell cycle as a consequence of receiving
multiple signals from elements found within their local environment. The first of these signals …

Unlike T cells that recognize digested peptides, B cells recognize their cognate antigen in its
native form. The B cell receptor used in recognition can also be secreted to bind to antigens …

The discovery that T cells cooperate with B cells in the induction of antibody production
marked a milestone in the study of immunology. Together with presentation of antigen by …