Patients with Systemic Lupus Erythematosus Show Increased Levels and Defective Function of CD69+ T Regulatory Cells

M Vitales-Noyola… - Mediators of …, 2017 - Wiley Online Library
T regulatory (Treg) cells have a key role in the pathogenesis of chronic inflammatory and
autoimmune diseases. A CD4+ CD69+ T cell subset has been described that behaves as …

Deficient CD4+ CD25high T regulatory cell function in patients with active systemic lupus erythematosus

X Valencia, C Yarboro, G Illei… - The Journal of …, 2007 - journals.aai.org
Abstract CD4+ CD25+ T regulatory cells (Tregs) play an essential role in maintaining
immunologic homeostasis and preventing autoimmunity. Systemic lupus erythematosus …

Phenotypic and functional analysis of CD4+ CD25− Foxp3+ T cells in patients with systemic lupus erythematosus

M Bonelli, A Savitskaya, CW Steiner, E Rath… - The Journal of …, 2009 - journals.aai.org
Abstract CD4+ CD25+ Foxp3+ regulatory T cells (Treg) that specialize in the suppression of
immune responses might be critically involved in the pathogenesis of autoimmune diseases …

Analysis of FOXP3+ regulatory T cell subpopulations in peripheral blood and tissue of patients with systemic lupus erythematosus

A Schmidt, CC Rieger, RK Venigalla, S Éliás… - Immunologic …, 2017 - Springer
Regulatory T cells (Tregs) are critical mediators of immune tolerance, yet their involvement
in the autoimmune disease systemic lupus erythematosus (SLE) is incompletely understood …

Regulatory T cells and their association with serum markers and symptoms in systemic lupus erythematosus and rheumatoid arthritis

V Kailashiya, U Singh, R Rana, NK Singh… - Immunological …, 2019 - Taylor & Francis
Purpose: Impairment in number and functions of regulatory T cells (Treg) has been found to
be associated with many autoimmune diseases including systemic lupus erythematosus …

Quantitative and qualitative deficiencies of regulatory T cells in patients with systemic lupus erythematosus (SLE)

M Bonelli, A Savitskaya, K Von Dalwigk… - International …, 2008 - academic.oup.com
The objective of the study was that the regulatory T cells (Treg) that specialize in the
suppression of immune responses might be critically involved in the pathogenesis of …

T-regulatory cells in systemic lupus erythematosus

A La Cava - Lupus, 2008 - journals.sagepub.com
Thymus-derived CD4+ CD25highFoxp3+ T-regulatory cells (Tregs) have an important role in
the mechanisms of peripheral immune tolerance and in the prevention of pathogenic …

T‑regulatory cells from patients with rheumatoid arthritis retain suppressor functions in vitro

D Shevyrev, V Tereshchenko… - Experimental and …, 2021 - spandidos-publications.com
Rheumatoid arthritis (RA) is a chronic disease of connective tissue caused by intolerance to
self‑antigens. Regulatory T cells (Tregs) are key players in maintaining autotolerance …

[HTML][HTML] The busy life of regulatory T cells in systemic lupus erythematosus

A La Cava - Discovery Medicine, 2009 - discoverymedicine.com
CD4+ CD25+ Foxp3+ regulatory T (Treg) cells suppress the proliferation and release of
cytokines in several subsets of immune cells. By doing so and by maintaining immune …

[HTML][HTML] The nature of increased circulating CD4+ CD25-Foxp3+ T cells in patients with systemic lupus erythematosus: a novel hypothesis

B Yan, Y Liu - The open rheumatology journal, 2009 - ncbi.nlm.nih.gov
The forkhead family transcriptional factor (Foxp3) is an important lineage marker for
regulatory T (Treg) cells. Foxp3 expression is primarily restricted to CD4+ CD25+ cell …