[HTML][HTML] The function of G-protein coupled receptors and membrane cholesterol: specific or general interaction?
YD Paila, A Chattopadhyay - Glycoconjugate journal, 2009 - Springer
Cholesterol is an essential component of eukaryotic membranes and plays a crucial role in
membrane organization, dynamics and function. The G-protein coupled receptors (GPCRs) …
membrane organization, dynamics and function. The G-protein coupled receptors (GPCRs) …
Allosteric modulation of GPCRs of class A by cholesterol
J Jakubík, EE El-Fakahany - International journal of molecular sciences, 2021 - mdpi.com
G-protein coupled receptors (GPCRs) are membrane proteins that convey extracellular
signals to the cellular milieu. They represent a target for more than 30% of currently …
signals to the cellular milieu. They represent a target for more than 30% of currently …
A critical analysis of molecular mechanisms underlying membrane cholesterol sensitivity of GPCRs
G protein-coupled receptors (GPCRs) are the largest and a diverse family of proteins
involved in signal transduction across biological membranes. GPCRs mediate a wide range …
involved in signal transduction across biological membranes. GPCRs mediate a wide range …
Role of cholesterol in the function and organization of G-protein coupled receptors
TJ Pucadyil, A Chattopadhyay - Progress in lipid research, 2006 - Elsevier
Cholesterol is an essential component of eukaryotic membranes and plays a crucial role in
membrane organization, dynamics and function. The modulatory role of cholesterol in the …
membrane organization, dynamics and function. The modulatory role of cholesterol in the …
Membrane cholesterol in the function and organization of G-protein coupled receptors
YD Paila, A Chattopadhyay - … Transport Proteins: Structure and Function in …, 2010 - Springer
Cholesterol is an essential component of higher eukaryotic membranes and plays a crucial
role in membrane organization, dynamics and function. The G-protein coupled receptors …
role in membrane organization, dynamics and function. The G-protein coupled receptors …
[HTML][HTML] Are specific nonannular cholesterol binding sites present in G-protein coupled receptors?
YD Paila, S Tiwari, A Chattopadhyay - Biochimica et Biophysica Acta (BBA) …, 2009 - Elsevier
The G-protein coupled receptors (GPCRs) are the largest class of molecules involved in
signal transduction across membranes, and represent major drug targets in all clinical …
signal transduction across membranes, and represent major drug targets in all clinical …
Cholesterol interaction motifs in G protein‐coupled receptors: Slippery hot spots?
P Sarkar, A Chattopadhyay - Wiley Interdisciplinary Reviews …, 2020 - Wiley Online Library
G protein‐coupled receptors (GPCRs) are cell membrane associated signaling hubs that
orchestrate a multitude of cellular functions upon binding to a diverse variety of extracellular …
orchestrate a multitude of cellular functions upon binding to a diverse variety of extracellular …
Cholesterol in Class C GPCRs: Role, relevance, and localization
G-protein coupled receptors (GPCRs), one of the largest superfamilies of cell-surface
receptors, are heptahelical integral membrane proteins that play critical roles in virtually …
receptors, are heptahelical integral membrane proteins that play critical roles in virtually …
GPCRs: Lipid‐dependent membrane receptors that act as drug targets
A Chattopadhyay - Advances in Biology, 2014 - Wiley Online Library
G protein‐coupled receptors (GPCRs) are the largest class of molecules involved in signal
transduction across cell membranes and represent major targets in the development of …
transduction across cell membranes and represent major targets in the development of …
Role of cholesterol-mediated effects in GPCR heterodimers
X Prasanna, M Mohole, A Chattopadhyay… - Chemistry and Physics …, 2020 - Elsevier
G protein-coupled receptors (GPCRs) are transmembrane receptors that mediate a large
number of cellular responses. The organization of GPCRs into dimers and higher-order …
number of cellular responses. The organization of GPCRs into dimers and higher-order …