Exosomes derived from mesenchymal stem cells: A promising cell-free therapeutic tool for cutaneous wound healing

A Zakeri, S Khaseb, MA Rahnama, A Hajaliaskari… - Biochimie, 2023 - Elsevier
Skin wound healing is a multifaceted process involving a cascade of molecular and cellular
procedures that occur in four different phases:(a) hemostasis,(b) inflammation,(c) …

Stem cells-derived exosomes alleviate neurodegeneration and Alzheimer's pathogenesis by ameliorating neuroinflamation, and regulating the associated molecular …

MI Khan, ES Jeong, MZ Khan, JH Shin, JD Kim - Scientific Reports, 2023 - nature.com
Amyloid beta (Aβ) aggregation and tau hyper phosphorylation (p-tau) are key molecular
factors in Alzheimer's disease (AD). The abnormal formation and accumulation of Aβ and p …

MAPK/AP-1 Signaling pathway is involved in the protection mechanism of bone marrow mesenchymal stem cells-derived exosomes against ultraviolet-induced …

T Yan, L Huang, Y Yan, Y Zhong, H Xie… - Skin Pharmacology and …, 2023 - karger.com
Introduction: The role of bone marrow mesenchymal stem cells-derived exosomes (BMSCs-
exo) in skin photoaging was explored in human dermal fibroblasts (HDFs). The underlying …

miR-204–containing exosomes ameliorate GVHD-associated dry eye disease

T Zhou, C He, P Lai, Z Yang, Y Liu, H Xu, X Lin, B Ni… - Science …, 2022 - science.org
Graft-versus-host disease (GVHD)–associated dry eye disease is characterized by extensive
inflammatory destruction in the ocular surface and causes unbearable pain and visual …

Lens epithelial cell‐derived exosome inhibits angiogenesis in ocular pathological neovascularization through its delivery of miR‐146a‐5p

T Pan, Y Wu, X Zhang, J Wang, X Wang… - The FASEB …, 2023 - Wiley Online Library
Abnormal ocular neovascularization, a major pathology of eye diseases, leads to severe
visual loss. The role of lens epithelial cell (LEC)‐derived exosomes (Lec‐exo) is largely …

Protective effect of intravitreal administration of exosomes derived from mesenchymal stem cells on retinal ischemia

E Moisseiev, JD Anderson, S Oltjen… - Current eye …, 2017 - Taylor & Francis
Purpose: Exosomes derived from human mesenchymal stem cells (hMSCs) cultured under
hypoxic conditions contain proteins and growth factors that promote angiogenesis. This …

Effects of mesenchymal stem cell-derived exosomes on experimental autoimmune uveitis

L Bai, H Shao, H Wang, Z Zhang, C Su, L Dong, B Yu… - Scientific reports, 2017 - nature.com
We previously demonstrated that mesenchymal stem cells (MSCs) ameliorated experimental
autoimmune uveoretinitis (EAU) in rats. Recently, MSC-derived exosomes (MSC-Exo) were …

[HTML][HTML] Mesenchymal stem cell derived exosomes-based immunological signature in a rat model of corneal allograft rejection therapy

Z Jia, Y Lv, W Zhang, X Zhang, F Li, X Lu… - Frontiers in Bioscience …, 2022 - imrpress.com
Background: Mesenchymal stem cells (MSCs) are promising candidates for
immunomodulatory therapy that are currently being tested in corneal allograft rejection. In …

The antisenescence effect of exosomes from human adipose‐derived stem cells on skin fibroblasts

JA Guo, PJ Yu, DQ Yang… - BioMed Research …, 2022 - Wiley Online Library
Human adipose‐derived stem cells (ADSCs) have become a promising therapeutic
approach against skin aging. Recent studies confirm that exosomes partially mediate the …

The molecular mechanism of human stem cell-derived extracellular vesicles in retinal repair and regeneration

M Yang, G Peng - Stem Cell Research & Therapy, 2023 - Springer
Extracellular vesicles (EVs), including microvesicles (MVs) and exosomes, play a critical role
in metabolic regulation and intracellular communication. Stem cell-derived EVs are …