Dear Editor, Treatment for optic nerve (ON) injury remains a challenge worldwide. As
essential paracrine signals of mesenchymal stem cells (MSCs), exosomes (exos) show …

Purpose This study aimed to investigate the effect of mesenchymal stem cell (MSC)-derived
small extracellular vesicles (sEVs) on diabetic retinopathy (DR) and its underlying …

Background Retinal and/or optic nerve injury is one of the leading causes of blindness due
to retinal ganglion cell (RGC) degeneration. There have been extensive efforts to suppress …

Exosomes are associated with the development and progression of Alzheimer's disease
(AD), although the impact of these extracellular vesicles in brain pathological condition …

Mesenchymal stem cells (MSCs)-based therapy has been reported to be a potential
approach to treat various diseases and the paracrine role might be the underlying …

Mesenchymal stem cell-derived exosomes have been under investigation as potential
treatments for a diverse range of diseases, and many animal and clinical trials have …

More and more evidence advises that circular RNAs (circRNAs) function critically in
regulating different disease microenvironments. Our previous study found that …

Elevated oxidative stress and associated reactive oxygen species (ROS) accumulation are
hallmarks in the induction and progression of age-related macular degeneration (AMD). By …

Background: Neurodegenerative diseases comprise a group of disorders for which no
treatment is available till date. Stem cell based therapy offers great hope and promise …

With the immunoregulation potential, mesenchymal stem cells (MSCs) have been used for
tissue regeneration by relieving inflammation in the injured tissues. When this repair process …