The identification of families with familial cancer syndromes would be relatively easy if all the
genes for these syndromes were known and all newly diagnosed cancer patients could be …

Although cancer predisposition syndromes are rare and malignancies arising in this context
account for only 1–10% of childhood tumors, studies performed in affected patients and their …

Hereditary cancer syndrome: Part 1.--Clinical and educational issues. - Abstract - Europe
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Abstract Geneticists estimate that 5% to 10% of all cancers diagnosed in the pediatric age
range occur in children born with a genetic mutation that directly increases their lifetime risk …

The biologic nature of tumors in childhood is clinically, histopathologically, and biologically
distinct from adult-onset malignancies. The vast majority of typical childhood cancers are …

Approximately 10% of all children with cancer are affected by a monogenic cancer
predisposition syndrome. This has important implications for both the child and her/his …

Henry T. Lynch, MD, Patrick M. Lynch, JD, William A. Albano, MD, John Edney, MD, Claude
H. Organ, MD and Jane F. Lynch, RN. drome that may be involved. As seen in the †œ …

The recent clinical availability of germ-line mutation testing for susceptibility genes related to
the hereditary forms of common tumors such as breast, ovary, colorectum, and melanoma …

Some details are inevitably lost when attempting to simplify subjects involving complex
medical genetics subjects. However, unless an attempt is made to distill such topics, busy …