Localization and developmental changes in prostaglandin H synthase (PGHS) and PGHS messenger ribonucleic acid in ovine placenta throughout gestation

W Gibb, SG Matthews, JRG Challis - Biology of reproduction, 1996 - academic.oup.com
In numerous animal species, increased prostaglandin output by intrauterine tissues occurs
in association with parturition. In the sheep, prostaglandin H synthase (PGHS) is particularly …

[PDF][PDF] Localization of prostaglandin synthase type-1 (PGHS-1) mRNA and prostaglandin synthase type-2 (PGHS-2) mRNA in ovine myometrium and endometrium …

W Gibb, M Sun, S Gyomorey, SJ Lye… - Journal of endocrinology, 2000 - Citeseer
Increased prostaglandin production by tissues in the sheep uterus and placenta are thought
to be important for the onset of parturition. In the sheep placenta, this is most likely due to …

Immunohistochemical localization of prostaglandin H synthase in the sheep placenta from early pregnancy to term

DP Boshier, RA Jacobs, VKM Han, W Smith… - Biology of …, 1991 - academic.oup.com
Prostaglandin H synthase (PGHS) activity within intrauterine tissues is considered to
catalyze a critical step in prostaglandin (PG) biosynthesis at parturition. In sheep, the …

Immunohistochemical localization of prostaglandin G/H synthase 1 and 2 in sheep placenta after glucocorticoid-induced and spontaneous labour.

WJ McLaren, IR Young, GE Rice - Journal of reproduction and …, 2000 - europepmc.org
Enhanced prostaglandin production and release by the placenta is an essential element in
the normal transition to labour in many animal species. In sheep, expression of …

[PDF][PDF] Increase in 15-hydroxyprostaglandin dehydrogenase activity in the ovine placentome at parturition and effect of oestrogen

SC Riley, R Leask, JV Selkirk, RW Kelly… - … of reproduction and …, 2000 - researchgate.net
Prostaglandin F2α (PGF2α) and PGE2 produced by the uterine tissues have long been
considered to be important during pregnancy for the regulation of blood flow (Carter, 1998) …

Gestational-and labour-associated changes in the relative abundance of prostaglandin G/H synthase-1 and-2 mRNA in ovine placenta

GE Rice, KA Freed, MA Aitken… - Journal of Molecular …, 1995 - jme.bioscientifica.com
The aim of this study was to establish the gestational-and labour-associated variation in the
relative abundance of prostaglandin synthase-1 (PGHS-1) and prostaglandin synthase-2 …

Fetal-to-Maternal Progression of Prostaglandin H2 Synthase-2 Expression in Ovine Intrauterine Tissues During the Course of Labor

S Gyomorey, SJ Lye, W Gibb… - Biology of …, 2000 - academic.oup.com
We examined whether spontaneous parturition in sheep was associated with tissue-specific
changes in prostaglandin H2 synthase-2 (PGHS-2) expression and/or with altered …

Expression of prostaglandin G/H synthase-1 and-2 in ovine amnion and placenta following glucocorticoid-induced labour onset

WJ McLaren, IR Young, MH Wong… - Journal of …, 1996 - joe.bioscientifica.com
Parturition in the sheep is preceded by an increase in the synthesis of prostaglandins by
intrauterine tissues. Prostaglandin G/H synthase (PGHS) is the central enzyme involved in …

[PDF][PDF] Localisation and temporal changes in prostaglandin G/H synthase-1 and-2 content in ovine intrauterine tissues in relation to glucocorticoid-induced and …

WJ McLaren, IR Young, GE Rice - Journal of Endocrinology, 2000 - Citeseer
Parturition in the ewe is preceded by an increase in the synthesis of prostaglandins (PGs) by
gestational tissues. To establish the uterine source of these PGs, placental cotyledons, fetal …

Immunoreactive prostaglandin G/H synthase content increases in ovine cotyledons during late gestation

GE Rice, MJ Payne, MH Wong, GD Thorburn - Placenta, 1992 - Elsevier
In this study, using gel electrophoresis and Western blotting, we have demonstrated that the
content of irPGHS in ovine placenta increases during late gestation prior to the onset of …