We now know our past concepts of AAA pathogenesis to be oversimplified and inaccurate.
In fact, the metabolic activity of the aneurysm wall is markedly increased in comparison with …

Abdominal aortic aneurysms (AAAs) are present in 8% of men 60 years of age. 1 The
diagnosis of AAA in many patients is made only after aneurysm rupture, after which mortality …

Abdominal aortic aneurysm (AAA) is a potentially fatal condition with risk of rupture
increasing as maximum AAA diameter increases. It is agreed upon that open surgical or …

Matrix metalloproteinases (MMPs) have been implicated in the pathogenesis of aortic
aneurysm because the histology of thoracic aortic aneurysm (TAA) and abdominal aortic …

The cardiovascular field is still searching for a treatment for abdominal aortic aneurysms
(AAA). This inflammatory disease often goes undiagnosed until a late stage and associated …

Despite advances in the treatment of abdominal aortic aneurysms (AAAs), the pathogenesis
of aneurysmal disease remains obscure. Aneurysm screening programmes have …

Aortic structure and function are controlled by the coordinated actions of different aortic cells
and the extracellular matrix. Several pathways have been identified that control the aortic …

A disturbance of the structure of the aortic wall results in the formation of aortic aneurysm,
which is characterized by a significant bulge on the vessel surface that may have …

Abdominal aortic aneurysm (AAA), a common disease among elderly individuals, involves
the progressive dilatation of the abdominal aorta as a consequence of degeneration. The …

OBJECTIVE: There is remarkable controversy over the processes driving abdominal
aneurysm growth. The inherent limitations of animal and human studies hamper elucidation …