Cancer cell plasticity includes their interconversion into various subtypes or entirely different
cells through transdifferentiation. This allows the cells to survive in difficult …

Lung cancer is the most common cause of cancer mortality worldwide. Non-small-cell lung
carcinomas (NSCLCs), which represent around 80% of lung tumors, exhibit poor prognosis …

The capacity of cancer cells for abnormal growth and metastasis has made it difficult to find a
cure for tumor. Both males and females suffer from lung tumors, and physicians still deem …

Wnt signal is known to play a significant role in many cellular processes such as cell
proliferation, survival, self-renewal, and differentiation. This pathway has been linked to …

The Wnt signal transduction pathway plays important roles during embryo development,
regulating cell proliferation and survival of immature cells. However, its improper function …

Evidence suggests that stem cells may be the source of mutant cells that cause cancers to
develop and proliferate. Wnt signaling has been shown to promote self-renewal in gut …

Non-small cell lung cancer (NSCLC) is the malignant tumor with the highest morbidity and
leading cause of death worldwide, whereas its pathogenesis has not been fully elucidated …

ABSTRACT Introduction: Wingless-type (Wnt) signaling is tightly regulated at multiple
cellular levels and is dysregulated in lung cancer. Therefore, it offers therapeutic targets for …

Significant advances in the treatment of non-small cell lung cancer (NSCLC) have been
made over the past decade, and they predominantly involve molecular targets such as …

Lung cancer is currently the leading cause of cancer mortality and morbidity worldwide and
greatly burdens humanity. Therefore, the prevention and treatment of lung cancer remains a …