Cilostazol-loaded electrospun three-dimensional systems for potential cardiovascular application: Effect of fibers hydrophilization on drug release, and …

M Rychter, B Milanowski, BF Grześkowiak… - Journal of colloid and …, 2019 - Elsevier
Currently marketed drug-eluting stents are non-selective in their anti-restenotic action. New
active substance introduction to polymeric stents and vascular grafts can promote early re …

[HTML][HTML] Cilostazol-loaded poly (ε-Caprolactone) electrospun drug delivery system for cardiovascular applications

M Rychter, A Baranowska-Korczyc, B Milanowski… - Pharmaceutical …, 2018 - Springer
Purpose The study discusses the value of electrospun cilostazol-loaded (CIL) polymer
structures for potential vascular implant applications. Methods Biodegradable …

Smart releasing electrospun nanofibers—poly: L. lactide fibers as dual drug delivery system for biomedical application

K Wulf, D Arbeiter, C Matschegewski… - Biomedical …, 2020 - iopscience.iop.org
An ongoing challenge in drug delivery systems for a variety of medical applications,
including cardiovascular diseases, is the delivery of multiple drugs to address numerous …

Multilayered electrospun fibrous meshes for restenosis‐suppressing metallic stents

YJ Son, HS Kim, DH Choi… - Journal of Biomedical …, 2017 - Wiley Online Library
Nanofiber is a flexible and highly porous mesh that is advantageous for coating bare metal
stent and local drug delivery. Herein, we developed drug‐eluting stent coated with PCL/PU …

Effect of the dissolution time into an acid hydrolytic solvent to tailor electrospun nanofibrous polycaprolactone scaffolds

O Gil-Castell, JD Badia, E Strömberg, S Karlsson… - European Polymer …, 2017 - Elsevier
The hydrolysis of the polycaprolactone (PCL) as a function of the dissolution time in a
formic/acetic acid mixture was considered as a method for tailoring the morphology of …

Influence of fibre diameter and orientation of electrospun copolyetheresterurethanes on smooth muscle and endothelial cell behaviour

C Rüder, T Sauter, K Kratz, T Haase… - Clinical …, 2013 - content.iospress.com
Polymers exhibiting cell-selective effects represent an extensive research field with high
relevance for biomedical applications eg in the cardiovascular field supporting re …

[HTML][HTML] Electrospun produced 3D matrices for covering of vascular stents: Paclitaxel release depending on fiber structure and composition of the external environment

KA Kuznetsov, AO Stepanova, RI Kvon, TEL Douglas… - Materials, 2018 - mdpi.com
Paclitaxel is a natural, highly lipophilic anti proliferative drug widely used in medicine. We
have studied the release of tritium-labeled paclitaxel (3H-PTX) from matrices destined for the …

[HTML][HTML] Fabrication of tri-layered electrospun polycaprolactone mats with improved sustained drug release profile

SM Kamath, K Sridhar, D Jaison, V Gopinath… - Scientific Reports, 2020 - nature.com
Modulation of initial burst and long term release from electrospun fibrous mats can be
achieved by sandwiching the drug loaded mats between hydrophobic layers of fibrous …

The effect of dipyridamole embedded in a drug delivery system made by electrospun nanofibers on aortic endothelial cells

A Repanas, A Bader, A Klett, A Ngezahayo… - Journal of Drug Delivery …, 2016 - Elsevier
An important sector of biomedical research is the generation of drug delivery systems
(DDSs), which can be used alone or integrated in stents for sustained drug release. In this …

[HTML][HTML] Accelerated endothelialization of nanofibrous scaffolds for biomimetic cardiovascular implants

C Matschegewski, S Kohse, J Markhoff, M Teske… - Materials, 2022 - mdpi.com
Nanofiber nonwovens are highly promising to serve as biomimetic scaffolds for pioneering
cardiac implants such as drug-eluting stent systems or heart valve prosthetics. For …