Resilience to amphetamine in mouse models of netrin-1 haploinsufficiency: role of mesocortical dopamine
M Pokinko, L Moquin, A Torres-Berrío, A Gratton… - …, 2015 - Springer
Rationale Signaling through the netrin-1 receptor, deleted in colorectal cancer (DCC), in
dopamine neurons controls the extent of their innervation to the medial prefrontal cortex …
dopamine neurons controls the extent of their innervation to the medial prefrontal cortex …
Abolition of the behavioral phenotype of adult netrin-1 receptor deficient mice by exposure to amphetamine during the juvenile period
L Yetnikoff, A Almey, A Arvanitogiannis, C Flores - Psychopharmacology, 2011 - Springer
Rationale Netrin-1 guidance cues contribute to amphetamine-induced plasticity of the adult
mesocorticolimbic dopamine system in rodents. The netrin-1 receptor, deleted in colorectal …
mesocorticolimbic dopamine system in rodents. The netrin-1 receptor, deleted in colorectal …
Netrin-1 receptor-deficient mice show age-specific impairment in drug-induced locomotor hyperactivity but still self-administer methamphetamine
Rationale The mesocorticolimbic dopamine system undergoes significant reorganization of
neuronal connectivity and functional refinement during adolescence. Deleted in colorectal …
neuronal connectivity and functional refinement during adolescence. Deleted in colorectal …
Dcc haploinsufficiency regulates dopamine receptor expression across postnatal lifespan
M Pokinko, A Grant, F Shahabi, Y Dumont, C Manitt… - Neuroscience, 2017 - Elsevier
Adolescence is a period during which the medial prefrontal cortex (mPFC) undergoes
significant remodeling. The netrin-1 receptor, deleted in colorectal cancer (DCC), controls …
significant remodeling. The netrin-1 receptor, deleted in colorectal cancer (DCC), controls …
Netrin‐1 receptor in the ventral tegmental area is required for sensitization to amphetamine
L Yetnikoff, C Eng, S Benning… - European Journal of …, 2010 - Wiley Online Library
Fundamental to neural organization during development, the netrin‐1 guidance cue and its
receptor, deleted in colorectal cancer (DCC), continue to be expressed in the adult brain. We …
receptor, deleted in colorectal cancer (DCC), continue to be expressed in the adult brain. We …
Regulation of netrin-1 receptors by amphetamine in the adult brain
L Yetnikoff, C Labelle-Dumais, C Flores - Neuroscience, 2007 - Elsevier
Netrin-1 is a guidance cue molecule fundamental to the organization of neuronal
connectivity during development. Netrin-1 and its receptors, deleted in colorectal cancer …
connectivity during development. Netrin-1 and its receptors, deleted in colorectal cancer …
Netrin receptor deficient mice exhibit functional reorganization of dopaminergic systems and do not sensitize to amphetamine
C Flores, C Manitt, D Rodaros, KM Thompson… - Molecular …, 2005 - nature.com
Netrins are guidance cues that play a fundamental role in organizing the developing brain.
The netrin receptor, DCC (deleted in colorectal cancer), is highly expressed by …
The netrin receptor, DCC (deleted in colorectal cancer), is highly expressed by …
Post‐pubertal emergence of a dopamine phenotype in netrin‐1 receptor‐deficient mice
A Grant, Z Speed, C Labelle‐Dumais… - European Journal of …, 2009 - Wiley Online Library
During the pubertal period the mesocortical dopamine (DA) system undergoes substantial
reorganization of neuronal connectivity and functional refinement. Netrins are guidance …
reorganization of neuronal connectivity and functional refinement. Netrins are guidance …
Netrin‐1 receptor‐deficient mice show enhanced mesocortical dopamine transmission and blunted behavioural responses to amphetamine
A Grant, D Hoops, C Labelle‐Dumais… - European Journal of …, 2007 - Wiley Online Library
The mesocorticolimbic dopamine (DA) system is implicated in neurodevelopmental
psychiatric disorders including schizophrenia but it is unknown how disruptions in brain …
psychiatric disorders including schizophrenia but it is unknown how disruptions in brain …
dcc Haploinsufficiency results in blunted sensitivity to cocaine enhancement of reward seeking
LM Reynolds, AJ Gifuni, ET McCrea, P Shizgal… - Behavioural brain …, 2016 - Elsevier
Mesocortical dopamine connectivity continues to mature during adolescence. This
protracted development confers increased vulnerability for environmental and genetic …
protracted development confers increased vulnerability for environmental and genetic …