Monocytosis and neutrophilia are frequent events in atherosclerosis. These phenomena
arise from the increased proliferation of hematopoietic stem and multipotential progenitor …

Introduction• Development of atherosclerotic plaques• Dyslipidaemia is a major risk factor for
atherosclerosis• Myeloid cells in atherosclerosis and effects of hyperlipidaemia–Monocytes …

Atherosclerosis is characterized by the progressive accumulation of lipids and leukocytes in
the arterial wall. Leukocytes such as macrophages accumulate oxidized lipoproteins in the …

Inflammation furnishes a series of pathogenic pathways that couple the risk factors for
atherosclerosis with altered behavior of the intrinsic cells of the arterial wall, endothelium …

Murphy and Tall Local Macrophage Proliferation in Atherosclerosis 237 not continue
indefinitely and that the macrophage pool of established lesions is ultimately derived from a …

Modulation of hematopoietic stem and progenitor cells (HSPCs) determines immune cell
function. In this study, we investigated how hypercholesterolemia affects HSPC biology and …

As the pathological basis of cardiovascular disease (CVD), atherosclerosis is featured as a
chronic inflammation. Hypercholesterolemia is an independent risk factor for CVD …

Atherosclerotic cardiovascular disease is a chronic inflammatory disease of the blood
vessels that can lead to myocardial infarction or stroke. The major cell in the atherosclerotic …

Atherosclerosis is a chronic inflammatory disease driven by lipids and other atherogenic
factors. It is characterized by a dynamic and complex pathological process of bone marrow …

Atherosclerosis is one of the leading causes of death and disability worldwide. It is a
complex disease characterized by lipid accumulation within the arterial wall, inflammation …