The host immune responses have been suggested toplay a role in liver injury occurring in
patients withchronic hepatitis C. In order to explore therelationship between the relative …

Antigen-specific T cells are likely to provide a critical defense against hepatitis C virus (HCV)
infection. However, their detection in blood is uncommon except in persons who undergo …

Background/aim: The mechanisms that determine the persistence or clearance of viral
infection in patients with chronic hepatitis C (CHC) are not well known. The goal of this study …

CD8+ lymphocytes of the memory subset (= CD45R0+) encompass antigen-specific effector
cells, which are believed to be decisive for virus elimination in several viral infections. To …

BACKGROUND & AIMS: In chronic hepatitis C (CHC), HCV-specific T-cell responses are
often dysfunctionnal. In vitro data point out that regulatory T cells (Treg) are able to suppress …

There is increasing interest in the role of T cell exhaustion and it is well known that the
natural history of chronic hepatitis C virus infection (HCV) is modulated by CD8+ T cell …

Autoimmune hepatitis (AIH) is characterized by dense T‐cell infiltrations in the liver tissue,
but little is known how T cells influence the pathogenesis. To address this question, the …

Aim The pathogenesis of viral hepatitis involves the activation of cellular immunity, including
intrahepatic lymphocytes (IHL). Lym-phocyte phenotypes play a fundamental role in the …

To ascertain whether the abnormalities of circulating T-cell subsets in patients with hepatitis
B virus (HBV)-related chronic liver diseases represent the primary immunological process or …

The activation state, differentiation state, and functions of liver lymphocytes and perihepatic
lymph nodes during chronic hepatitis C virus (HCV) infection are not well understood. Here …