Maintenance of genome integrity is a precise but tedious and complex job for the cell.
Several post-translational modifications (PTMs) play vital roles in maintaining the genome …

A dynamic array of histone post-translational modifications (PTMs) regulate diverse cellular
processes in the eukaryotic chromatin. Among them, histone ubiquitination is particularly …

Chromatin functions are influenced by the addition, removal, and recognition of histone post-
translational modifications (PTMs). Ubiquitin and ubiquitin-like (UBL) PTMs on histone …

Histone post-transcriptional modifications play essential roles in regulation of all DNA
related processes. Among them, histone ubiquitination has been discovered for more than …

Myriad covalent post-translational modifications of histones have been demonstrated to play
crucial roles in regulating gene transcription, gene repression, DNA damage and repair, and …

Post-translational modifications of the histones are centrally involved in the regulation of all
DNA-templated processes, including gene transcription, DNA replication, recombination …

Recently, many of the enzymes responsible for the addition and removal of ubiquitin from
the histones H2A and H2B have been identified and characterized. From these studies, it …

Post-translational modifications (PTMs) play important roles in almost every aspect of
biological processes through modulating protein–protein interaction, subcellular …

Complex mechanisms are in place to maintain genome stability. Ubiquitination of chromatin
plays a central role in these mechanisms. The ever-growing complexity of the ubiquitin (Ub) …

Monoubiquitination of histone H2B has emerged as an important chromatin modification
with roles not only in transcription but also in cell differentiation, DNA repair or mRNA …