Introduction Vitamin D supplementation has been suggested to enhance immunity during
respiratory infection season. We tested the effect of active vitamin D (calcitriol) …

Vitamin D is a regulator of host defense against infections and induces expression of the
antimicrobial peptide hCAP18/LL-37. Vitamin D deficiency is associated with chronic …

The prevalence of vitamin D insufficiency and deficiency has increased markedly in recent
decades to current epidemic levels (Hyppönen E, et al. Am J Clin Nutr 2007; 85: 860–868) …

Background Vitamin D deficiency has been implicated as a factor in a number of infectious
and inflammatory lung diseases. In the lung, alveolar macrophages play a key role in …

Over the past decade, interest has grown in the effects of vitamin D on respiratory infections
and obstructive airway diseases (OADs), such as asthma and chronic obstructive pulmonary …

Over the past decade, interest has grown in the role of vitamin D in many nonskeletal
medical conditions, including respiratory infection. Emerging evidence indicates that vitamin …

Background Early studies indicated that vitamin D (VD) exerted pleiotropic extra-skeletal
effects in the airway, but the definite linkage between VD deficiency and airway host …

Cigarette smoking is associated with increased inflammation and defective antibacterial
responses in the airways. Interestingly, vitamin D has been shown to suppress inflammation …

Vitamin D plays a key role in the human immune response to infections. Vitamin D induces
the production of the antimicrobial polypeptide cathelicidin (hCAP18/LL37)(1), which has …

Chronic airway inflammatory and infectious respiratory diseases are the most common
medical respiratory conditions, associated with significant morbidity and mortality. Vitamin D …