Abstract Captopril (1 and 4 mg/kg) was administered intravenously to rabbits and plasma
converting enzyme measured using a radioenzymatic technique. Captopril inhibited plasma …

The kinetics of captopril plasma levels and of the drug‐induced plasma converting enzyme
activity (PCEA), plasma renin activity (PRA) and diastolic blood pressure (DBP) …

Captopril (Capoten) hasbeen evaluated in the treatment both of hypertension and cardiac
failure (Atkinson & Robertson, 1979). However, it is currently indicated only for severe or …

A sensitive assay is described for quantitating plasma captopril levels. Captopril is an orally
active inhibitor of angiotensin-con-verting enzyme. Blood from patients taking this drug was …

Intravenous Captopril (20 μg) in rats produced similar inhibition of the pressor responses to
intravenous ANG I (70%) and of plasma-converting enzyme activity (CEA) measured …

Abstract Captopril (SQ 14 225) was administered to normotensive, sodium-replete
volunteers in order to investigate the relationships between its haemodynamic effects and …

Intraveneus administration of captopril (20 μg) produced inhibition of angiotensin I pressor
responses by 70 percent and of plasma-converting enzyme activity by 72 percent. Oral …

The effects of captopril on blood pressure and plasma angiotensin-converting enzyme were
studied in cats with two-kidney, one-clip experimental hypertension. The time period for the …

1. The relationship between the antihypertensive action of captopril and its inhibitory effect
on angiotensin I (ANG I)-converting enzyme has been investigated. Converting enzyme was …

The disposition of Captopril, an angiotensin‐converting enzyme inhibitor with
antihypertensive properties, was studied in 10 normal male subjects after a single 100‐mg …