Upregulation of the nitrosylome in bipolar disorder type 1 (BP1) and major depression, but not BP2: Increased IgM antibodies to nitrosylated conjugates are …
M Maes, D Simeonova, D Stoyanov, JC Leunis - Nitric Oxide, 2019 - Elsevier
Objective Major depression (MDD) and a lifetime history of MDD are characterized by
increased nitrosylation, while bipolar disorder type 1 (BP1), but not BP2, is accompanied by …
increased nitrosylation, while bipolar disorder type 1 (BP1), but not BP2, is accompanied by …
Major differences in neurooxidative and neuronitrosative stress pathways between major depressive disorder and types I and II bipolar disorder
M Maes, K Landucci Bonifacio, NR Morelli… - Molecular …, 2019 - Springer
Accumulating evidence indicates that oxidative and nitrosative stress (O&NS) pathways play
a key role in the pathophysiology of bipolar disorder (BD) and major depressive disorder …
a key role in the pathophysiology of bipolar disorder (BD) and major depressive disorder …
Construction of a nitro-oxidative stress-driven, mechanistic model of mood disorders: A nomothetic network approach
D Simeonova, D Stoyanov, JC Leunis, M Murdjeva… - Nitric Oxide, 2021 - Elsevier
Major depression is accompanied by increased IgM-mediated autoimmune responses to
oxidative specific epitopes (OSEs) and nitric oxide (NO)-adducts. These responses were not …
oxidative specific epitopes (OSEs) and nitric oxide (NO)-adducts. These responses were not …
Common environmental factors may underpin the comorbidity between generalized anxiety disorder and mood disorders via activated nitro-oxidative pathways
C Roomruangwong, DS Simeonova… - Current topics in …, 2018 - ingentaconnect.com
Generalized Anxiety Disorder (GAD) commonly co-occurs with mood disorders, especially
Major Depressive Disorder (MDD) and bipolar disorder (BD), which are accompanied by …
Major Depressive Disorder (MDD) and bipolar disorder (BD), which are accompanied by …
Increased autoimmune responses against auto-epitopes modified by oxidative and nitrosative damage in depression: implications for the pathways to chronic …
M Maes, M Kubera, I Mihaylova, M Geffard… - Journal of affective …, 2013 - Elsevier
OBJECTIVE: There is evidence that major depression is characterized by oxidative and
nitrosative stress (O&NS). The aim of this study is to examine IgM-mediated autoimmune …
nitrosative stress (O&NS). The aim of this study is to examine IgM-mediated autoimmune …
Increased serum immunoglobulin responses to gut commensal Gram-negative bacteria in unipolar major depression and bipolar disorder type 1, especially when …
D Simeonova, D Stoyanov, JC Leunis… - Neurotoxicity …, 2020 - Springer
Major depressive disorder (MDD) is accompanied by higher serum IgM/IgA responses to
LPS of Gram-negative bacteria, suggesting increased bacterial translocation and gut …
LPS of Gram-negative bacteria, suggesting increased bacterial translocation and gut …
Bipolar disorder: role of immune-inflammatory cytokines, oxidative and nitrosative stress and tryptophan catabolites
G Anderson, M Maes - Current psychiatry reports, 2015 - Springer
Bipolar disorder (BD) is a complex disorder with a range of presentations. BD is defined by
the presentation of symptoms of mania or depression, with classification dependent on …
the presentation of symptoms of mania or depression, with classification dependent on …
Oxidative & nitrosative stress in depression: why so much stress?
S Moylan, M Berk, OM Dean, Y Samuni… - Neuroscience & …, 2014 - Elsevier
Many studies support a crucial role for oxidative & nitrosative stress (O&NS) in the
pathophysiology of unipolar and bipolar depression. These disorders are characterized inter …
pathophysiology of unipolar and bipolar depression. These disorders are characterized inter …
Multi-level biomarker analysis of nitric oxide synthase isoforms in bipolar disorder and adult ADHD
S Kittel-Schneider, M Reuß, A Meyer… - Journal of …, 2015 - journals.sagepub.com
Introduction: Several studies have shown altered levels of nitric oxide (NO) and its stable
metabolites (NOx-) in blood and cerebrospinal fluid of psychiatric patients. The aim of our …
metabolites (NOx-) in blood and cerebrospinal fluid of psychiatric patients. The aim of our …
The role of the arginine-nitric oxide pathway in the pathogenesis of bipolar affective disorder
There is a reciprocal regulation of arginase and nitric oxide synthase (NOS) in L-arginine-
metabolizing pathways. Nitric oxide (NO) may be involved in some psychiatric disorders like …
metabolizing pathways. Nitric oxide (NO) may be involved in some psychiatric disorders like …