Trisubstituted thiazoles were synthesized and studied for their antimicrobial activity and
supported by theoretical calculations. In addition, MIC, MBC and MFC were also tested …

Discovery of novel anticandidal agents with clarified mechanisms of action, could be a
rationalist approach against diverse pathogenic fungal strains due to the rise of resistance to …

In this study the green, one-pot, solvent-free and selective synthesis of benzimidazole
derivatives is reported. The reactions were catalyzed by ZnO/MgO containing ZnO …

Molecular docking simulation of thirty-five (35) molecules of N-(2-phenoxy) ethyl imidazo [1,
2-a] pyridine-3-carboxamide (IPA) with Mycobacterium tuberculosis target (DNA gyrase) was …

Fungal infections have become a serious medical problem due to the high infection rate and
the frequent emergence of drug resistance. Squalene epoxidase (SE) and 14α-demethylase …

In this investigation, a series of piperazine sulfynol derivatives 5 (al) were synthesized and
amply characterized by various spectral techniques viz, LC-MS, 1 H NMR, 13 C NMR, and …

Benzimidazole is a valuable pharmacophore in the field of medicinal chemistry and exhibit
wide spectrum of biological activity. Molecular docking technique is routinely used in …

In this study 12 novel benzimidazole compounds bearing hydrazone moiety were
synthesized in order to investigate their possible antibacterial and antifungal activity …

A new series of N-aryl-4-(1, 3-diaryl-1H-pyrazol-4-yl) thiazol-2-amine,(8a-x) have been
synthesized by a cyclo-condensation reaction of 2-bromo-1-(1, 3-diphenyl-1H-pyrazol-4-yl) …

Candida albicans infections and their resistance to clinically approved azole drugs are
major concerns for human. The azole antifungal drugs inhibit the ergosterol synthesis by …