Fixed-dose combination therapy in hypertension: cons
The goal of antihypertensive therapy is to reduce the risk associated with blood pressure
elevation. Although the choice of first-line drug therapy may exert some effects on different …
elevation. Although the choice of first-line drug therapy may exert some effects on different …
Fixed and low-dose combinations of blood pressure-lowering agents: for the many or the few?
Despite the widespread availability of several effective classes of drugs, systemic arterial
hypertension remains poorly controlled in the majority of patients worldwide. In this article …
hypertension remains poorly controlled in the majority of patients worldwide. In this article …
Issues in blood pressure control and the potential role of single‐pill combination therapies
M Burnier, RE Brown, SH Ong… - … journal of clinical …, 2009 - Wiley Online Library
Hypertension (HTN) is a major risk factor for cardiovascular mortality, yet only a small
proportion of hypertensive individuals receive appropriate therapy and achieve target blood …
proportion of hypertensive individuals receive appropriate therapy and achieve target blood …
More medications, fewer pills: combination medications for the treatment of hypertension
R Lewanczuk, SW Tobe - Canadian journal of cardiology, 2007 - Elsevier
Achieving blood pressure targets in hypertension can be challenging. Often, patients require
multiple medications to reach these targets. The Canadian Hypertension Education Program …
multiple medications to reach these targets. The Canadian Hypertension Education Program …
Improving blood pressure control rates by optimizing combination antihypertensive therapy
BJ Epstein - Expert opinion on pharmacotherapy, 2010 - Taylor & Francis
Importance of the field: Hypertension is the most common preventable cause of
cardiovascular morbidity and mortality. Despite the availability of a multitude of …
cardiovascular morbidity and mortality. Despite the availability of a multitude of …
Combination drug treatment of hypertension: have we come full circle?
AA Taylor - Current Cardiology Reports, 2004 - Springer
Only 30% of hypertensive patients achieved and maintained adequate blood pressure
control on a single drug in recent clinical trials. For the majority of patients who require two …
control on a single drug in recent clinical trials. For the majority of patients who require two …
Creating a combination antihypertensive regimen: what does the research show?
MA Weber - The Journal of Clinical Hypertension, 2003 - Wiley Online Library
Major randomized clinical trials have demonstrated unquestionable clinical benefits of
lowering blood pressure without establishing superiority of any specific antihypertensive …
lowering blood pressure without establishing superiority of any specific antihypertensive …
New approach to blood pressure control: triple combination pill
Blood pressure (BP) control remains insufficient worldwide, mostly due to poor adherence to
treatments, clinical inertia, adverse effects and underuse of drug-combination strategies …
treatments, clinical inertia, adverse effects and underuse of drug-combination strategies …
Use of single-pill combination therapy in the evolving paradigm of hypertension management
DA Calhoun - Expert Opinion on Pharmacotherapy, 2009 - Taylor & Francis
The use of antihypertensive therapy is an evolving paradigm. Although blood pressure (BP)
control rates remain low, there have been improvements that may be attributable in part to a …
control rates remain low, there have been improvements that may be attributable in part to a …
Using fixed-dose combination therapies to achieve blood pressure goals
SG Chrysant - Clinical drug investigation, 2008 - Springer
Hypertension affects an estimated 88 million Americans and is controlled to the
recommended blood pressure (BP) goal of< 140/90 mmHg in only 37% of individuals with …
recommended blood pressure (BP) goal of< 140/90 mmHg in only 37% of individuals with …