Short time exposure to lipopolysaccharide is sufficient to activate human monocytes.
P Gallay, CV Jongeneel, C Barras… - … (Baltimore, Md.: 1950 …, 1993 - journals.aai.org
Very little is known about early events in LPS binding and about the duration of LPS
exposure required to activate monocytes. In the present study, we have investigated the …
exposure required to activate monocytes. In the present study, we have investigated the …
Control of lipopolysaccharide (LPS) binding and LPS-induced tumor necrosis factor secretion in human peripheral blood monocytes.
D Heumann, P Gallay, C Barras, P Zaech… - … (Baltimore, Md.: 1950 …, 1992 - journals.aai.org
We used flow cytometry to determine how LPS-binding protein (LBP) effects the binding of
fluorescein-labeled LPS to human monocytes via receptor-dependent mechanisms. The …
fluorescein-labeled LPS to human monocytes via receptor-dependent mechanisms. The …
Lipopolysaccharide (LPS) partial structures inhibit responses to LPS in a human macrophage cell line without inhibiting LPS uptake by a CD14-mediated pathway.
RL Kitchens, RJ Ulevitch, RS Munford - The Journal of experimental …, 1992 - rupress.org
Lipopolysaccharides (LPS) that lack acyloxyacyl groups can antagonize responses to LPS
in human cells. Although the site and mechanism of inhibition are not known, it has been …
in human cells. Although the site and mechanism of inhibition are not known, it has been …
Isolation of a macrophage-like cell line defective in binding of lipopolysaccharide. Influence of serum and lipopolysaccharide chain length on macrophage activation.
T Kirikae, FU Schade, F Kirikae… - … (Baltimore, Md.: 1950 …, 1993 - journals.aai.org
A mutant cell line (J7. DEF. 3) derived from murine macrophage-like J774. 1 cells, was
isolated on the basis of defective specific 125I-labeled LPS-binding in the presence of …
isolated on the basis of defective specific 125I-labeled LPS-binding in the presence of …
Lipopolysaccharide (LPS) stimulates fresh human monocytes to lyse actinomycin D-treated WEHI-164 target cells via increased secretion of a monokine similar to …
AR Chen, KP McKinnon, HS Koren - Journal of immunology …, 1985 - journals.aai.org
We have studied the effects of lipopolysaccharide (LPS) on tumoricidal activity of human
monocytes freshly isolated from peripheral blood. Actinomycin D-treated WEHI-164 cells …
monocytes freshly isolated from peripheral blood. Actinomycin D-treated WEHI-164 cells …
Enhanced production of LPS-induced cytokines during differentiation of human monocytes to macrophages. Role of LPS receptors.
S Gessani, U Testa, B Varano, P Di Marzio… - … (Baltimore, Md.: 1950 …, 1993 - journals.aai.org
In vitro cultivated human monocytes isolated from normal peripheral blood show a time-
dependent differentiation into macrophages characterized by an increased expression of …
dependent differentiation into macrophages characterized by an increased expression of …
Tumor necrosis factor release from lipopolysaccharide-stimulated human monocytes: lipopolysaccharide tolerance in vitro
M Matic, SR Simon - Cytokine, 1991 - Elsevier
Human peripheral blood monocytes secrete tumor necrosis factor (TNF) in response to
stimulation with bacterial lipopolysaccharide (LPS). We have shown that isolated human …
stimulation with bacterial lipopolysaccharide (LPS). We have shown that isolated human …
Preexposure of macrophages to low doses of lipopolysaccharide inhibits the expression of tumor necrosis factor-alpha mRNA but not of IL-1 beta mRNA.
N Takasuka, T Tokunaga… - Journal of immunology …, 1991 - journals.aai.org
LPS is known to be a potent activator of macrophages and induces the production of TNF-
alpha and IL-1. However, the signaling events and regulatory mechanisms required for the …
alpha and IL-1. However, the signaling events and regulatory mechanisms required for the …
Binding, internalization, and deacylation of bacterial lipopolysaccharide by human neutrophils.
M Luchi, RS Munford - Journal of immunology (Baltimore, Md.: 1950 …, 1993 - journals.aai.org
Bacterial LPS is a potent agonist for priming and stimulating neutrophils (PMN). Although
much has recently been learned about the binding receptors for LPS on these and other …
much has recently been learned about the binding receptors for LPS on these and other …
Effects of site-directed mutagenesis of basic residues (Arg 94, Lys 95, Lys 99) of lipopolysaccharide (LPS)-binding protein on binding and transfer of LPS and …
N Lamping, A Hoess, B Yu, TC Park… - … (Baltimore, Md.: 1950 …, 1996 - journals.aai.org
LPS-binding protein (LBP) is a 60-kDa acute phase glycoprotein capable of binding the LPS
of Gram-negative bacteria and facilitating its diffusion. This process is thought to be of …
of Gram-negative bacteria and facilitating its diffusion. This process is thought to be of …