Acute coronary syndromes are a spectrum of clinical presentations with various
pathophysiology substrates. As such it is impossible to talk about one type of atherosclerotic …

Advances in coronary imaging are needed to enable the early detection of plaque segments
considered to be'vulnerable'for causing clinical events. Pathological studies have …

This study was undertaken to verify the hypothesis that the discrepant findings in published
reports on the prevalence of thrombus in unstable angina depend on the inclusion of …

Background Postmortem-derived findings support the common beliefs that lipid-rich
coronary plaques with a thin, fibrous cap are prone to rupture and that rupture and …

T he clinical transition from chronic to acute coronary syndromes, including unstable angina
and acute myocardial infarction, is attributed to dynamic changes in the composition and …

Intravascular ultrasound (IVUS) has a defined role in the cardiac catheterization laboratory
to assess lesion severity and the procedural success of vascular interventions. However …

OBJECTIVES To determine the morphologic features of coronary plaques associated with
acute coronary syndrome, we prospectively followed patients with atherosclerotic disease …

Coronary artery disease remains one of the leading causes of morbidity and mortality in the
United States. As a medical society, we continue to search for ways to better treat coronary …

Rupture of vulnerable plaques is the main cause of acute coronary syndromes and
myocardial infarctions. Identification of these vulnerable plaques is therefore essential to …

Background—Previous studies have reported diffuse destabilization of atherosclerotic
plaques in acute myocardial infarction (AMI). Methods and Results—We used intravascular …