Activation of Nuclear Factor of Activated T Cells by Human T-Lymphotropic Virus Type 1 Accessory Protein p12I

B Albrecht, CD D'Souza, W Ding… - Journal of …, 2002 - Am Soc Microbiol
Human T-lymphotropic virus type 1 (HTLV-1) is the agent of an aggressive malignancy of
CD4+ T lymphocytes, called adult T-cell lymphoma/leukemia, and is associated with …

Human T-Cell Lymphotropic Virus Type 1 p12I Enhances Interleukin-2 Production during T-Cell Activation

W Ding, SJ Kim, AM Nair, B Michael… - Journal of …, 2003 - Am Soc Microbiol
Human T-cell lymphotropic virus type 1 (HTLV-1) causes adult T-cell leukemia/lymphoma
(ATLL) and a variety of lymphoproliferative disorders. The early virus-cell interactions that …

[HTML][HTML] A conserved calcineurin-binding motif in human T lymphotropic virus type 1 p12I functions to modulate nuclear factor of activated T cell activation

S Kim, W Ding, B Albrecht, PL Green… - Journal of Biological …, 2003 - ASBMB
The PXIXIT calcineurin binding motif or highly related sequences are found in a variety of
calcineurin-binding proteins in yeast, mammalian cells, and viruses. The accessory protein …

Human T-Cell Lymphotropic Virus Type 1 p12I Expression Increases Cytoplasmic Calcium To Enhance the Activation of Nuclear Factor of Activated T Cells

W Ding, B Albrecht, RE Kelley, N Muthusamy… - Journal of …, 2002 - Am Soc Microbiol
Human T-cell lymphotropic virus type 1 (HTLV-1) establishes persistent infection and is
associated with lymphoproliferative or neurodegenerative diseases. As a complex retrovirus …

Inhibition of T-Cell Receptor Signal Transduction and Viral Expression by the Linker for Activation of T Cells-Interacting p12I Protein of Human T-Cell Leukemia …

R Fukumoto, M Dundr, C Nicot, A Adams… - Journal of …, 2007 - Am Soc Microbiol
The p12I protein of human T-cell leukemia/lymphoma virus type 1 (HTLV-1) is a small
oncoprotein that increases calcium release following protein kinase C activation by phorbol …

Enhancement of LFA-1-mediated T cell adhesion by human T lymphotropic virus type 1 p12I1

S Kim, AM Nair, S Fernandez, L Mathes… - The Journal of …, 2006 - journals.aai.org
Cell-to-cell transmission of retroviruses, such as human T lymphotropic virus type 1 (HTLV-
1), is well documented, but the roles of viral regulatory or other nonstructural proteins in the …

Proliferation response to interleukin-2 and Jak/Stat activation of T cells immortalized by human T-cell lymphotropic virus type 1 is independent of open reading frame I …

ND Collins, C D'Souza, B Albrecht, MD Robek… - Journal of …, 1999 - Am Soc Microbiol
Human T-cell lymphotropic virus type 1 (HTLV-1), a complex retrovirus, encodes a
hydrophobic 12-kD protein from pX open reading frame (ORF) I that localizes to cellular …

Human T-cell leukemia virus type 1 p8 protein increases cellular conduits and virus transmission

N Van Prooyen, H Gold, V Andresen… - Proceedings of the …, 2010 - National Acad Sciences
The human T-cell leukemia virus type 1 (HTLV-1) is the cause of adult T-cell
leukemia/lymphoma as well as tropical spastic paraparesis/HTLV-1–associated myelopathy …

[HTML][HTML] Human T lymphotropic virus type-1 p30II alters cellular gene expression to selectively enhance signaling pathways that activate T lymphocytes

B Michael, AM Nair, H Hiraragi, L Shen, G Feuer… - Retrovirology, 2004 - Springer
Background Human T-lymphotropic virus type-1 (HTLV-1) is a deltaretrovirus that causes
adult T-cell leukemia/lymphoma and is implicated in a variety of lymphocyte-mediated …

Human T-cell leukemia/lymphoma virus type 1 p30, but not p12/p8, counteracts toll-like receptor 3 (TLR3) and TLR4 signaling in human monocytes and dendritic cells

C Fenizia, M Fiocchi, K Jones, RW Parks… - Journal of …, 2014 - Am Soc Microbiol
The human T-cell leukemia/lymphoma virus type 1 (HTLV-1) p30 protein, essential for virus
infectivity in vivo, is required for efficient infection of human dendritic cells (DCs) but not B …