* Address correspondence to: PJM van Galen, NIH/NIDDK, Building 8A, Room B1A-17,
Bethesda, MD 20892; telephone 301-496-9024; fax 301-402-0008. Medicinal Research …

Investigation of the physiologic role of the A3 adenosine receptor has been facilitated by the
availability of selective agonists and antagonists. Selective agonists include IB‐MECA and …

In this review, Joel linden summarizes what is known about a new and intriguing member of
the adenosine receptor family, the A3 receptor. This receptor exhibits unusually large …

Adenosine is an endogenous nucleoside that modulates many physiological processes. Its
actions are mediated by interaction with specific cell membrane receptors. Four subtypes of …

To examine the importance of the nine native cysteine residues in the human A1 adenosine
receptor, each cysteine was individually mutated to both serine and alanine. Saturation …

BACKGROUND The present invention relates to substituted 5-amino pyrazolo-4, 3-e-1, 2, 4-
triazolo 1, 5-cpyrimidine adenosine A receptor antagonists, the use of Said compounds in …

Adenosine produces a wide variety of effects throughout the body via activation of cell
surface adenosine receptors. Adenosine receptors belong to the family of seven …

We have previously reported the selective amplification of several rat striatal cDNA
sequences that encode guanine nucleotide-binding regulatory protein (G protein)-coupled …

Adenosine receptor (AR) agonists and antagonists are approximately 100-fold and 100,000-
fold, respectively, more potent at the bovine A1AR as compared to the rat A3AR. To …

The A1 adenosine receptor is the best characterized of the widely distributed purinergic
receptor family. The purified brain A1 receptor is a monomeric 35‐to 36‐kDa glycoprotein …