Synthetic polycaprolactone (PCL) was modified with various concentrations of gelatin (GL)
to enhance its physical properties and biological activity for bone regeneration. A novel …

Numerous clinical bone disorders, such as infections and bone loss from cancer or trauma,
increase the need for bone regeneration. Due to the difficulty of self-repairing large bone …

Fish bone extract (FBE) containing a trioligopeptide (FBP‐KSA, Lys‐Ser‐Ala) isolated from
Johnius belengerii could induce osteogenic activities on MC3T3‐E1 pre‐osteoblasts in our …

Bone tissue engineering has been developed in the past decades, with the engineering of
bone substitutes on the vanguard of this regenerative approach. Polycaprolactone-based …

Synthetic biomaterials combined with cells and osteogenic factors represent a promising
approach for the treatment of a number of orthopedic diseases, such as bone trauma and …

A solid structure similar to an extracellular matrix network is needed for bone cells
attachment and starting healing of bone damages. Different biomaterials and fabrication …

Our research was designed to evaluate the effect on bone regeneration with 3-dimensional
(3D) printed polylactic acid (PLA) and 3D printed polycaprolactone (PCL) scaffolds …

Critical-sized bone defects are a major challenge in reconstructive bone surgery and usually
fail to be treated due to limited remaining bone quality and extensive healing time. The …

Abstract Treatment of large bone defects is challenging and requires coordination between
cells, cytokines, and mechanical demands. Scaffold for bone tissue engineering should …

Biodegradable polycaprolactone (PCL) scaffolds made by fused deposition modeling (FDM)
were coated with a layer of calcium phosphate using a biomimetic method and seeded with …