Rotaviruses: from pathogenesis to vaccination

HB Greenberg, MK Estes - Gastroenterology, 2009 - Elsevier
Rotaviruses cause life-threatening gastroenteritis in children worldwide; the enormous
disease burden has focused efforts to develop vaccines and led to the discovery of novel …

Pathogenesis of intestinal and systemic rotavirus infection

RF Ramig - Journal of virology, 2004 - Am Soc Microbiol
Rotaviruses are responsible for significant gastrointestinal disease, primarily in children 5
years of age and the young of other mammalian species. Each year rotaviruses cause …

[HTML][HTML] Rotavirus vaccines: recent developments and future considerations

J Angel, MA Franco, HB Greenberg - Nature reviews microbiology, 2007 - nature.com
Two new vaccines have recently been shown to be safe and effective in protecting young
children against severe rotavirus gastroenteritis. Although both vaccines are now marketed …

[HTML][HTML] Rotaviruses: From pathogenesis to disease control—A critical review

CA Omatola, AO Olaniran - Viruses, 2022 - mdpi.com
Since their first recognition in human cases about four decades ago, rotaviruses have
remained the leading cause of acute severe dehydrating diarrhea among infants and young …

The rotavirus vaccine story: from discovery to the eventual control of rotavirus disease

RI Glass, JE Tate, B Jiang… - The Journal of Infectious …, 2021 - academic.oup.com
Worldwide, rotavirus is the leading pathogen causing severe diarrhea in children and a
major cause of under 5 years mortality. In 1998, the first rotavirus vaccine, RotaShield, was …

Rotavirus disease and its prevention

MA Widdowson, JS Bresee, JR Gentsch… - Current Opinion in …, 2005 - journals.lww.com
Rotavirus disease and its prevention : Current Opinion in Gastroenterology Rotavirus disease
and its prevention : Current Opinion in Gastroenterology Log in or Register Subscribe to …

[HTML][HTML] Rotavirus infections and vaccines: burden of illness and potential impact of vaccination

K Grimwood, SB Lambert, RJ Milne - Pediatric drugs, 2010 - Springer
Rotaviruses are the most common cause of severe gastroenteritis in children. By 5 years of
age virtually every child worldwide will have experienced at least one rotavirus infection …

Rotavirus vaccines: opportunities and challenges

K Grimwood, SB Lambert - Human vaccines, 2009 - Taylor & Francis
Each year rotavirus gastroenteritis episodes in young children cause more than 500,000
deaths and 2.4 million hospital admissions worldwide. Vaccine development became a …

Product review of the rotavirus vaccines ROTASIIL, ROTAVAC, and Rotavin-M1

A Skansberg, M Sauer, M Tan… - Human Vaccines & …, 2021 - Taylor & Francis
Rotavirus is the leading cause of severe dehydrating gastroenteritis and death due to
diarrhea among children under 5, causing over 180,000 under-5 deaths annually. Safe …

[HTML][HTML] Rotavirus infection

SE Crawford, S Ramani, JE Tate… - Nature Reviews …, 2017 - nature.com
Rotavirus infections are a leading cause of severe, dehydrating gastroenteritis in children< 5
years of age. Despite the global introduction of vaccinations for rotavirus over a decade ago …