Serum biomarkers correlated with liver stiffness assessed in a multicenter study of pediatric cholestatic liver disease

DH Leung, S Devaraj, NP Goodrich, X Chen… - Hepatology, 2023 - journals.lww.com
Conclusions: Endoglin, IL‐8, and MMP‐7 significantly correlate with increased LSM in
children with BA, whereas CTGF inversely correlates with LSM in participants with A1AT; …

[PDF][PDF] Nonfasted liver stiffness correlates with liver disease parameters and portal hypertension in pediatric cholestatic liver disease

BL Shneider, NP Goodrich, W Ye… - Hepatology …, 2020 - Wiley Online Library
Elastographic measurement of liver stiffness is of growing importance in the assessment of
liver disease. Pediatric experiences with this technique are primarily single center and …

Hepatic inflammation may influence liver stiffness measurements by transient elastography in children and young adults

A Raizner, N Shillingford, PD Mitchell… - Journal of pediatric …, 2017 - journals.lww.com
Objectives: Transient elastography (TE) measures liver stiffness to assess fibrosis. Studies in
adults have shown that inflammation increases stiffness, leading to an overestimation of …

Normal liver stiffness and influencing factors in healthy children: An individual participant data meta‐analysis

DK Li, MR Khan, Z Wang, V Chongsrisawat… - Liver …, 2020 - Wiley Online Library
Abstract Background & Aims Although transient elastography (TE) is used to determine liver
stiffness as a surrogate to hepatic fibrosis, the normal range in children is not well defined …

[HTML][HTML] Transient elastography-based liver stiffness age-dependently increases in children

D Tokuhara, Y Cho, H Shintaku - PloS one, 2016 - journals.plos.org
Background and Aims Pediatric use of liver transient elastography (TE) is attractive for its
non-invasiveness, but reference values have not been established. We aimed to determine …

[PDF][PDF] The discriminatory ability of FibroScan liver stiffness measurement, controlled attenuation parameter, and FibroScan–aspartate aminotransferase to predict …

A Chaidez, Z Pan, SS Sundaram… - Hepatology …, 2022 - Wiley Online Library
Vibration controlled transient elastography (FibroScan) is used to predict the severity of liver
fibrosis and steatosis. In pediatrics, few studies have been performed directly comparing …

Transient liver elastography in unsedated control children: Impact of age and intercurrent illness

PJ Lewindon, F Balouch, TN Pereira… - … of Paediatrics and …, 2016 - Wiley Online Library
Aim Transient elastography (TE) is a rapid, non‐invasive, reproducible assessment of liver
fibrosis by liver stiffness measurement (LSM). Uncertainty remains regarding utility in …

[PDF][PDF] “Normal” liver stiffness measure (LSM) values are higher in both lean and obese individuals: a population‐based study from a developing country

K Das, R Sarkar, SM Ahmed, AR Mridha… - …, 2012 - Wiley Online Library
The liver stiffness measure (LSM) needs to be explored in ethnically and anthropometrically
diverse healthy subjects (to derive an acceptable normal range) and also in patients with …

[HTML][HTML] Is there an association between commonly employed biomarkers of liver fibrosis and liver stiffness in the general population?

FG Foschi, M Domenicali, P Giacomoni… - Annals of …, 2020 - Elsevier
Introduction and objectives Surrogate biomarkers of liver fibrosis developed in tertiary care
are increasingly used in general populations. We evaluated the association between liver …

[HTML][HTML] Normal liver stiffness values in children: a comparison of three different elastography methods

AB Mjelle, A Mulabecirovic, RF Havre… - Journal of pediatric …, 2019 - journals.lww.com
Objectives: Noninvasive tests for the evaluation of liver fibrosis are particularly helpful in
children to avoid general anesthesia and potential complications of invasive tests. We aimed …