Genome-wide association studies (GWAS) have identified over 70 loci associated with type
2 diabetes (T2D). Most genetic variants associated with T2D are common variants with …

Genome-wide association (GWAS) and sequencing studies are providing new insights into
the genetic basis of type 2 diabetes (T2D) and the inter-individual variation in glycemic traits …

Type 2 diabetes is one of the most common complex diseases, of which considerable efforts
have been made to unravel the pathophysiological mechanisms. Recently, large‐scale …

The discovery of the association between HLA in the major histocompatibility complex
(MHC) on chromosome 6p21 with type 1 diabetes, but not with type 2 diabetes, suggested …

As with other complex diseases, unbiased association studies followed by physiological and
experimental characterization have for years formed a paradigm for identifying genes or …

Despite numerous candidate gene and linkage studies, the field of type 2 diabetes (T2D)
genetics had until recently succeeded in identifying few genuine disease-susceptibility loci …

Over the past 8 years, the genetics of complex traits have benefited from an unprecedented
advancement in the identification of common variant loci for diseases such as type 2 …

Genetic and environmental factors as well as their interactions contribute to the
pathogenesis of type 2 diabetes. Linkage analysis, candidate gene approaches, genome …

Type 1 diabetes (T1D) is classically characterised by the clinical need for insulin, the
presence of disease-associated serum autoantibodies, and an onset in childhood. The …

Type 2 diabetes is a genetically heterogeneous disease, with several relatively rare
monogenic forms and a number of more common forms resulting from a complex interaction …