Review of current machine perfusion therapeutics for organ preservation

J Xu, JE Buchwald, PN Martins - Transplantation, 2020 - journals.lww.com
Because of the high demand of organs, the usage of marginal grafts has increased. These
marginal organs have a higher risk of developing ischemia-reperfusion injury, which can …

The future of organ perfusion and re‐conditioning

A Weissenbacher, G Vrakas, D Nasralla… - Transplant …, 2019 - Wiley Online Library
Organ preservation and re‐conditioning using machine perfusion technologies continue to
generate promising results in terms of viability assessment, organ utilization and improved …

Bioengineering approaches to organ preservation ex vivo

M Pinezich… - Experimental Biology and …, 2019 - journals.sagepub.com
The advent of successful solid organ transplantation is undoubtedly among the most
significant medical achievements of the 20th century. Despite advances in the field of …

[HTML][HTML] Machine perfusion for abdominal organ preservation: a systematic review of kidney and liver human grafts

MI Bellini, M Nozdrin, J Yiu, V Papalois - Journal of Clinical Medicine, 2019 - mdpi.com
Introduction: To match the current organ demand with organ availability from the donor pool,
there has been a shift towards acceptance of extended criteria donors (ECD), often …

[HTML][HTML] Organ preservation: from the past to the future

L Jing, L Yao, M Zhao, L Peng, M Liu - Acta Pharmacologica Sinica, 2018 - nature.com
Organ transplantation is the most effective therapy for patients with end-stage disease.
Preservation solutions and techniques are crucial for donor organ quality, which is directly …

Machine perfusion or cold storage in organ transplantation: indication, mechanisms, and future perspectives

X Yuan, AJ Theruvath, X Ge… - Transplant …, 2010 - Wiley Online Library
Most organs are currently preserved by cold storage (CS) prior to transplantation. However,
as more so called marginal donor organs are utilized, machine perfusion has regained …

Machine perfusion of donor organs for transplantation

R Tatum, TJ O'Malley, AS Bodzin… - Artificial …, 2021 - Wiley Online Library
The ever‐widening gap between organ supply and demand has resulted in an organ
shortage crisis that affects patients all over the world. For decades, static cold storage (SCS) …

Hypothermic ex situ perfusion of human limbs with acellular solution for 24 hours

V Haug, B Kollar, S Tasigiorgos, Y Endo… - …, 2020 - journals.lww.com
Background. Machine perfusion (MP) has evolved as a promising approach for the ex situ
preservation in organ transplantation. However, the literature on the use of MP in human …

Machine perfusion in organ transplantation: a tool for ex-vivo graft conditioning with mesenchymal stem cells?

D Van Raemdonck, A Neyrinck, F Rega… - Current opinion in …, 2013 - journals.lww.com
Machine perfusion of solid organs has regained much attention during the last decade. It
provides a new promising tool that may allow pretransplant ex-vivo assessment …

[HTML][HTML] Ex-vivo Kidney Machine Perfusion: Therapeutic Potential

R Zulpaite, P Miknevicius, B Leber, K Strupas… - Frontiers in …, 2021 - frontiersin.org
Kidney transplantation remains the gold standard treatment for patients suffering from end-
stage kidney disease. To meet the constantly growing organ demands grafts donated after …