ID proteins may reduce aggressiveness of thyroid tumors
LHP Amaral, NE Bufalo, KC Peres, IS Barreto… - Endocrine …, 2019 - Springer
ID genes have an important function in the cell cycle, and ID proteins may help identify
aggressive tumors, besides being considered promising therapeutic targets. However, their …
aggressive tumors, besides being considered promising therapeutic targets. However, their …
Id1 gene expression is up-regulated in hyperplastic and neoplastic thyroid tissue and regulates growth and differentiation in thyroid cancer cells
E Kebebew, M Peng, PA Treseler… - The Journal of …, 2004 - academic.oup.com
The Id (i nhibitor of D NA binding) proteins are a family of helix-loop-helix (HLH) proteins
(Id1, Id2, Id3, and Id4) that lack the basic domain necessary for DNA binding. The Id1 protein …
(Id1, Id2, Id3, and Id4) that lack the basic domain necessary for DNA binding. The Id1 protein …
The helix-loop-helix protein, Id-1, is overexpressed and regulates growth in papillary thyroid cancer
E Kebebew, PA Treseler, QY Duh, OH Clark - Surgery, 2003 - Elsevier
Background. Members of the Id helix-loop-helix proteins are key regulators of cell growth
and differentiation in a variety of cell types. They are also required for cell cycle progression …
and differentiation in a variety of cell types. They are also required for cell cycle progression …
The helix-loop-helix transcription factor, Id-1, is overexpressed in medullary thyroid cancer
E Kebebew, PA Treseler, QY Duh, OH Clark - Surgery, 2000 - Elsevier
Background. The Id-1 helix-loop-helix protein inhibits differentiation and enhances cell
proliferation. It is required for cell cycle progression. The Id-1 gene is highly expressed in a …
proliferation. It is required for cell cycle progression. The Id-1 gene is highly expressed in a …
Id1 gene expression and regulation in human thyroid tissue
E Kebebew - Thyroid, 2005 - liebertpub.com
The Id genes encode helix-loop-helix (HLH) transcription proteins that lack a DNA binding
basic domain. Id proteins (Id1, Id2, Id3, and Id4) function as dominant negative regulators of …
basic domain. Id proteins (Id1, Id2, Id3, and Id4) function as dominant negative regulators of …
[HTML][HTML] Id proteins expression in prostate cancer: high-level expression of Id-4 in primary prostate cancer is associated with development of metastases
HF Yuen, CW Chua, YP Chan, YC Wong, X Wang… - Modern pathology, 2006 - Elsevier
A major cause of treatment failure for prostate cancer is the development of androgen-
independent metastatic disease. Id protein family, a group of basic helix–loop–helix …
independent metastatic disease. Id protein family, a group of basic helix–loop–helix …
Letter Re: Id1 gene expression in hyperplastic and neoplastic thyroid tissues
AS Rao, PE Goretzki, J Köhrle… - The Journal of Clinical …, 2005 - academic.oup.com
The molecular signatures of cancer cells have recently been delineated in more detail.
There exist distinct differences in the molecular characteristics of cells derived from a …
There exist distinct differences in the molecular characteristics of cells derived from a …
Inhibitor of DNA binding-1 induces mesenchymal features and promotes invasiveness in thyroid tumour cells
A Ciarrocchi, S Piana, R Valcavi, G Gardini… - European Journal of …, 2011 - Elsevier
Characterisation of molecular mechanisms that control tumour invasion is a crucial step for
the identification of molecular markers to apply in cancer diagnosis and treatment. In this …
the identification of molecular markers to apply in cancer diagnosis and treatment. In this …
Id-1 and Id-2 are overexpressed in pancreatic cancer and in dysplastic lesions in chronic pancreatitis
H Maruyama, J Kleeff, S Wildi, H Friess… - The American journal of …, 1999 - Elsevier
Id proteins antagonize basic helix-loop-helix proteins, inhibit differentiation, and enhance
cell proliferation. In this study we compared the expression of Id-1, Id-2, and Id-3 in the …
cell proliferation. In this study we compared the expression of Id-1, Id-2, and Id-3 in the …
Reassessment of id1 protein expression in human mammary, prostate, and bladder cancers using a monospecific rabbit monoclonal anti-id1 antibody
J Perk, I Gil-Bazo, Y Chin, P de Candia, JJS Chen… - Cancer research, 2006 - AACR
Id proteins are a class of dominant-negative antagonists of helix-loop-helix transcription
factors and have been shown to control differentiation of a variety of cell types in diverse …
factors and have been shown to control differentiation of a variety of cell types in diverse …