The pathogenic mechanism of severe acute pancreatitis complicated with renal injury: a review of current knowledge
XP Zhang, L Wang, YF Zhou - Digestive diseases and sciences, 2008 - Springer
The onset of severe acute pancreatitis (SAP) is clinically harmful as it may rapidly progress
from a local pancreatic inflammation into proemial systemic inflammatory reactions. Patients …
from a local pancreatic inflammation into proemial systemic inflammatory reactions. Patients …
Experimental models of acute pancreatitis: are they suitable for evaluating therapy?
T Foitzik, HG Hotz, G Eibl, HJ Buhr - International journal of colorectal …, 2000 - Springer
Since randomized controlled studies of severe acute human pancreatitis can be performed
only with restrictions, at least some aspects of innovative therapy concepts should first be …
only with restrictions, at least some aspects of innovative therapy concepts should first be …
Molecular mechanisms of pancreatic injury
Current findings have provided further insight into the roles and mechanisms of zymogen
activation and inflammatory pathways in pancreatic injury. Future studies, which will be of …
activation and inflammatory pathways in pancreatic injury. Future studies, which will be of …
Pathogenic mechanisms of acute pancreatitis
New findings necessitate a paradigm shift in our understanding of acute pancreatitis. Intra-
acinar trypsinogen activation leads to early pancreatic injury, but the inflammatory response …
acinar trypsinogen activation leads to early pancreatic injury, but the inflammatory response …
[HTML][HTML] Do animal models of acute pancreatitis reproduce human disease?
FS Gorelick, MM Lerch - Cellular and molecular gastroenterology and …, 2017 - Elsevier
Acute pancreatitis is currently the most common cause of hospital admission among all
nonmalignant gastrointestinal diseases. To understand the pathophysiology of the disease …
nonmalignant gastrointestinal diseases. To understand the pathophysiology of the disease …
[HTML][HTML] Prediction of severe acute pancreatitis: current knowledge and novel insights
GI Papachristou - World journal of gastroenterology: WJG, 2008 - ncbi.nlm.nih.gov
Acute pancreatitis (AP) is a common and potentially lethal acute inflammatory process with a
highly variable clinical course. It is still unclear why some patients progress to organ failure …
highly variable clinical course. It is still unclear why some patients progress to organ failure …
Experimental animal models of acute pancreatitis.
MM Lerch, G Adler - … journal of pancreatology: official journal of the …, 1994 - europepmc.org
Experimental animal models have been employed to study pancreatitis for more than a
century. Although not always related to the disease in humans, they have contributed greatly …
century. Although not always related to the disease in humans, they have contributed greatly …
Etiopathogenesis of acute pancreatitis
S Karne, FS Gorelick - Surgical Clinics of North America, 1999 - Elsevier
Acute pancreatitis (AP) is a disease characterized by abdominal pain and elevations in the
serum levels of amylase and lipase. 27 A key feature of AP is the elaboration of an …
serum levels of amylase and lipase. 27 A key feature of AP is the elaboration of an …
New insights into acute pancreatitis
PJ Lee, GI Papachristou - Nature reviews Gastroenterology & …, 2019 - nature.com
The incidence of acute pancreatitis continues to increase worldwide, and it is one of the
most common gastrointestinal causes for hospital admission in the USA. In the past decade …
most common gastrointestinal causes for hospital admission in the USA. In the past decade …
Update on the management of acute pancreatitis
FF van den Berg, MA Boermeester - Current Opinion in Critical …, 2023 - journals.lww.com
More treatment modalities that are less invasive became available and a trend towards less
aggressive treatments (fluids, starvation, interventions, opiates) of acute pancreatitis is again …
aggressive treatments (fluids, starvation, interventions, opiates) of acute pancreatitis is again …