The incidence of acute pancreatitis continues to increase worldwide, and it is one of the
most common gastrointestinal causes for hospital admission in the USA. In the past decade …

Severe acute pancreatitis (SAP), which is the most serious type of this disorder, is
associated with high morbidity and mortality. SAP runs a biphasic course. During the first 1-2 …

Acute pancreatitis is a common clinical condition. The exact mechanisms by which diverse
etiological factors induce an attack are unclear but once the disease process is initiated …

Inflammatory mediators play a key role in acute pancreatitis and the resultant multiple organ
dysfunction syndrome, which is the primary cause of death in this condition. Recent studies …

INTRODUCTION—Acute pancreatitis is an common inflammatory condition of the pancreas
characterized clinically by abdominal pain and elevated levels of pancreatic enzymes in the …

Acute pancreatitis (AP) is a common acute inflammatory process of the pancreas that affects
approximately 80,000 individuals in the United States annually [1]. The clinical course of AP …

Introduction 3. Biology of the exocrine pancreas 4. Early events in acute pancreatitis 4.1.
Cellular localization of the early events 4.2. Co-localization theory 4.3. Trypsinogen …

The mortality of severe acute pancreatitis still ranges between 10 and 20%. Nowadays,
infected pancreatic necrosis is the leading cause of death. Despite advances in intensive …

Objective. Acute pancreatitis (AP) is an inflammatory disorder that develops a complex
cascade of immunological events. The local and systemic immune status and inflammatory …

Severe acute pancreatitis (SAP) develops in about 25% of patients with acute pancreatitis
(AP). Severity of AP is linked to the presence of systemic organ dysfunctions and/or …