Reduced-antigen-content pertussis vaccines designed initially for booster vaccination of
adolescents and adults can also be used to vaccinate pre-school age children. Combination …

As vaccine-induced immunity and protection following natural pertussis infection wane over
time, adults and adolescents may develop pertussis and become transmitters to unprotected …

Reduced-antigen-content diphtheria–tetanus–acellular-pertussis (dTpa) vaccines are
predominantly recommended for once-in-a-lifetime use. A second dTpa (Boostrix™ …

Pertussis vaccines containing reduced amounts of antigen have been considered primarily
for use in adolescents and adults to date. We evaluated a reduced antigen content …

Background: Due to the resurgence of pertussis, many countries have revised the pertussis
immunization schedules and recommended booster doses of pertussis component vaccine …

Aim To evaluate the immunogenicity and safety of a reduced antigen diphtheria-tetanus-
acellular pertussis-inactivated poliovirus (dTap-IPV B) vaccine (Boostrix-IPV, GSK) as a pre …

A trial to compare the reactogenicity and immunogenicity of a reduced antigen content
diphtheria–tetanus–acellular pertussis (dTpa) vaccine with diphtheria–tetanus–whole-cell …

BACKGROUND: Increasing incidence of pertussis in adolescents and adults has stimulated
the development of safe and immunogenic acellular pertussis vaccines for booster …

Background: Pertussis occurs in older children, adolescents and adults due to waning
immunity after primary vaccination. Booster vaccination for pre-school children has been …

Background Transplacentally transferred antibodies induced by maternal pertussis
vaccination interfere with infant immune responses to pertussis primary vaccination. We …