Metastasis is not the result of a random event, as cancer cells can sustain and proliferate
actively only in a suitable tissue microenvironment and then form metastases. Since Dr …

Cancer treatment with ionizing radiation (IR) is a well-established and effective clinical
method to fight different types of tumors and is a palliative treatment to cure metastatic …

The microenvironmental physiology of tumors is uniquely different from that of normal
tissues. It is characterized, inter alia, by O2 depletion (hypoxia, anoxia), glucose and energy …

Radiation therapy has been used worldwide for many decades as a therapeutic regimen for
the treatment of different types of cancer. Just over 50% of cancer patients are treated with …

Radiotherapy plays a central part in curing cancer. For decades, most research on
improving treatment outcomes has focused on modulating radiation-induced biological …

Ionizing radiation (IR), such as X-rays and gamma (γ)-rays, mediates various forms of cancer
cell death such as apoptosis, necrosis, autophagy, mitotic catastrophe, and senescence …

Radiation therapy is a highly effective method for inhibiting tumor growth and is widely used
in clinical settings. 1 It damages the vital biomolecules (especially DNA) of cancer cells and …

Purpose: To present and evaluate clinical data suggesting that cancer metastasis may be
induced by the microenvironment of the primary tumour and to discuss possible …

Radiotherapy (RT), besides cancer cells, also affects the tumor microenvironment (TME):
tumor blood vessels and cells of the immune system. It damages endothelial cells and …

Simple Summary Cancer is multifaceted and consists of more than just a collection of
mutated cells. These cancerous cells reside along with other non-mutated cells in an …